Boc-LRR-AMC (trifluoroacetate salt)

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Boc-LRR-AMC (trifluoroacetate salt) Basic information
Product Name:Boc-LRR-AMC (trifluoroacetate salt)
Synonyms:Boc-LRR-AMC (trifluoroacetate salt)
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
Boc-LRR-AMC (trifluoroacetate salt) Structure
Boc-LRR-AMC (trifluoroacetate salt) Chemical Properties
solubility DMF: 14 mg/ml
DMSO: 12 mg/ml
Ethanol: 10 mg/mlPBS (pH 7.2): 1 mg/ml
Safety Information
MSDS Information
Boc-LRR-AMC (trifluoroacetate salt) Usage And Synthesis
DescriptionBoc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core.1,2 Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify 26S proteasome or 20S proteolytic core trypsin-like activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.WARNING This product is not for human or veterinary use.
References[1] IGOR M PRUDNIKOV; Anton N S. Short peptide tools for monitoring caspase and proteasome activities in embryonal and adult rat brain lysates: an approach for the differential identification of proteases.[J]. Journal of biochemistry, 2012, 151 3: 299-316. DOI: 10.1093/jb/mvs001
[2] Yashi Anyun. Interferon-γ induces different subunit organizations and functional diversity of proteasomes[C]. 1900: 0. DOI: 10.11501/3073770
Boc-LRR-AMC (trifluoroacetate salt) Preparation Products And Raw materials
Tag:Boc-LRR-AMC (trifluoroacetate salt) Related Product Information
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