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| | N-methyl-N-(2,2,2-trifluoroethyl)amine hydrochloride Basic information |
| Product Name: | N-methyl-N-(2,2,2-trifluoroethyl)amine hydrochloride | | Synonyms: | N-methyl-N-(2,2,2-trifluoroethyl)amine hydrochloride;2,2,2-TRIFLUORO-N-METHYLETHANAMINIUM CHLORIDE;Methyl(2,2,2-trifluoroethyl)aMine, HCl;N-Methyl-N-(2,2,2-trifluoroethyl)aMine HCl;2,2,2-Trifluoro-N-MethylethanaMine HCl;N-Methyl-2,2,2-trifluoroethylamine Hydrochloride;Ethanamine, 2,2,2-trifluoro-N-methyl-, hydrochloride (1:1);2,2,2-trifluoro-N-methyl-Ethanamine hydrochloride (1:1) | | CAS: | 2730-52-1 | | MF: | C3H7ClF3N | | MW: | 149.54 | | EINECS: | | | Product Categories: | | | Mol File: | 2730-52-1.mol |  |
| | N-methyl-N-(2,2,2-trifluoroethyl)amine hydrochloride Chemical Properties |
| Melting point | >200 °C (sublm)(Solv: ethanol (64-17-5)) | | storage temp. | Inert atmosphere,Room Temperature | | form | solid | | color | White | | InChI | InChI=1S/C3H6F3N.ClH/c1-7-2-3(4,5)6;/h7H,2H2,1H3;1H | | InChIKey | CUOWKFXFKFXJEL-UHFFFAOYSA-N | | SMILES | C(CNC)(F)(F)F.[H]Cl |
| WGK Germany | WGK 3 | | HazardClass | IRRITANT | | HS Code | 2921199990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2 |
| | N-methyl-N-(2,2,2-trifluoroethyl)amine hydrochloride Usage And Synthesis |
| Synthesis | General procedure for the synthesis of N-methyl-2,2,2-trifluoroacetamide hydrochloride from N-methyl-2,2,2-trifluoroacetamide: A solution was prepared by dissolving lithium aluminum hydride (69 g, 1.8 mol) in 100 mL of ether at 100 °C. To this solution, an ether solution of 2,2,2-trifluoro-N-methylacetamide (86 g, 0.6 mol) was slowly added at 0 °C. The reaction mixture was stirred at room temperature overnight. Subsequently, sodium sulfate decahydrate was added to the mixture at -10°C and the resulting suspension was filtered. Dry HCl gas was passed into the filtrate until a white solid precipitated. The solid product was separated by filtration and recrystallized with a solvent mixture of methanol/ether to give N-methyl-2,2,2-trifluoroethylamine hydrochloride as a final white solid (73 g, 80.7% yield). | | References | [1] Patent: WO2010/131145, 2010, A1. Location in patent: Page/Page column 76 |
| | N-methyl-N-(2,2,2-trifluoroethyl)amine hydrochloride Preparation Products And Raw materials |
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