|
|
| | Tetrakis(hydroxymethyl)phosphonium chloride Basic information |
| | Tetrakis(hydroxymethyl)phosphonium chloride Chemical Properties |
| Melting point | 154°C | | Boiling point | 115°C/760mmHg | | density | 1.341 g/mL at 25 °C | | vapor pressure | 0Pa at 25℃ | | refractive index | n20/D 1.512 | | pka | 6.05[at 20 ℃] | | form | Solution | | color | Clear light pink or yellow-green | | Water Solubility | >=10 g/100 mL at 20 ºC | | BRN | 3631669 | | InChI | InChI=1S/C4H12O4P.ClH/c5-1-9(2-6,3-7)4-8;/h5-8H,1-4H2;1H/q+1;/p-1 | | InChIKey | AKXUUJCMWZFYMV-UHFFFAOYSA-M | | SMILES | [P+](CO)(CO)(CO)CO.[Cl-] | | LogP | -9.8 | | CAS DataBase Reference | 124-64-1(CAS DataBase Reference) | | EPA Substance Registry System | Tetrakis(hydroxymethyl)phosphonium chloride (124-64-1) |
| Hazard Codes | T,N | | Risk Statements | 21-25-38-41-42/43-51/53 | | Safety Statements | 22-26-36/37/39-45-60-61-23 | | RIDADR | UN 2810 6.1/PG 3 | | WGK Germany | 3 | | RTECS | TA2450000 | | TSCA | TSCA listed | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29319019 | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 3 Dermal
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
Met. Corr. 1
Repr. 1B
Skin Corr. 1B
Skin Sens. 1 | | Hazardous Substances Data | 124-64-1(Hazardous Substances Data) | | Toxicity | mammal (species unspecified),LD50,oral,400mg/kg (400mg/kg),Kobunshi. High Polymers. Vol. 24, Pg. 788, 1975. |
| | Tetrakis(hydroxymethyl)phosphonium chloride Usage And Synthesis |
| Chemical Properties | Clear light pink or yellow-green solution | | Uses | Flame-retarding agent for cotton fabrics. May
be used in combination with triethylolamine and
urea (Roxel process) or with triethanolamine and
tris(1-aziridinyl) phosphine oxide. | | Uses | Tetrakis(hydroxymethyl)phosphonium chloride solution (80% in H2O) has been used as a reducing agent and stabilizing ligand for the synthesis of gold nanoparticles (AuNPs) from gold(III) chloride trihydrate (HAuCl4.3H2O). It is a tetra-functional, amine-reactive, aqueous crosslinker that can be used for tuning the properties of protein-based hydrogels for 3D cell encapsulation applications. | | Definition | A crystalline compound made by the reaction of
phosphine, formaldehyde, and hydrochloric acid. | | General Description | Clear slightly viscous,colorless to yellow liquid (20% H2O solution). | | Air & Water Reactions | Hygroscopic. Water soluble. | | Reactivity Profile | Tetrakis(hydroxymethyl)phosphonium chloride reacts vigorously with oxidizers and alkalis. Reacts with cellulose. | | Health Hazard | ACUTE/CHRONIC HAZARDS: Tetrakis(hydroxymethyl)phosphonium chloride may be corrosive. When heated to decomposition, it may emit very toxic fumes of POx, hydrogen chloride and bis(chloromethyl)ether. Decomposition of Tetrakis(hydroxymethyl)phosphonium chloride in an aqueous environment may produce phosphine, formaldehyde and hydrogen chloride. | | Fire Hazard | Tetrakis(hydroxymethyl)phosphonium chloride is probably combustible. | | Flammability and Explosibility | Non flammable | | Purification Methods | Crystallise it from AcOH and dry it at 100o in a vacuum. An 80% w/v aqueous solution has d4 1.33 [Reeves J Am Chem Soc 77 3923 1955]. [Beilstein 1 IV 3062.] |
| | Tetrakis(hydroxymethyl)phosphonium chloride Preparation Products And Raw materials |
|