- Boldine
-
- $35.00 / 25mg
-
2026-02-27
- CAS:476-70-0
- Min. Order:
- Purity: 98.53%
- Supply Ability: 10g
- Boldine
-
- $1.00 / 1KG
-
2025-12-12
- CAS:476-70-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 420000KG
- Boldine
-
- $1.00 / 1KG
-
2019-07-06
- CAS: 476-70-0
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 100KG
|
| | Boldine Basic information |
| Product Name: | Boldine | | Synonyms: | (+)-(s)-boldine;(s)-boldine;(s)-yl;1,10-dimethoxy-6a-alpha-aporphine-2,9-diol;1,10-dimethoxy-6a-alpha-aporphine-9-diol;4h-dibenzo(de,g)quinoline-2,9-diol,5,6,6a,7-tetrahydro-1,10-dimethoxy-6-meth;4h-dibenzo[de,g]quinoline-2,9-diol,5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl;boldin | | CAS: | 476-70-0 | | MF: | C19H21NO4 | | MW: | 327.37 | | EINECS: | 207-509-9 | | Product Categories: | | | Mol File: | 476-70-0.mol |  |
| | Boldine Chemical Properties |
| Melting point | 162-164 °C | | Boiling point | 465.27°C (rough estimate) | | density | 1.2223 (rough estimate) | | refractive index | 1.5000 (estimate) | | storage temp. | 2-8°C | | solubility | Acetonitrile (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly) | | pka | 9.75±0.20(Predicted) | | form | Solid | | color | Yellow to Dark Brown | | Merck | 13,1316 | | BRN | 94036 | | Major Application | food and beverages
forensics and toxicology
veterinary | | InChI | 1S/C19H21NO4/c1-20-5-4-10-7-15(22)19(24-3)18-12-9-16(23-2)14(21)8-11(12)6-13(20)17(10)18/h7-9,13,21-22H,4-6H2,1-3H3/t13-/m0/s1 | | InChIKey | LZJRNLRASBVRRX-ZDUSSCGKSA-N | | SMILES | COc1cc-2c(CC3N(C)CCc4cc(O)c(OC)c-2c34)cc1O | | LogP | 0.837 (est) | | CAS DataBase Reference | 476-70-0(CAS DataBase Reference) | | EPA Substance Registry System | 4H-Dibenzo[de,g]quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (6aS)- (476-70-0) |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 1-20-24/25-45-36-26 | | RIDADR | 1544 | | WGK Germany | 3 | | RTECS | CE0750000 | | TSCA | TSCA listed | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 29399990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | Boldine Usage And Synthesis |
| Chemical Properties | White powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Linderae odorata. | | Uses | antineoplastic | | Uses | boldine is attributed with strong anti-oxidant properties. It has also demonstrated an ability to protect against uVB rays. Boldine is a constituent of the boldo plant (Peumus boldus Mol.) native to Chile, and is found in the plant’s leaves and bark. | | Definition | ChEBI: Boldine is an aporphine alkaloid. | | in vivo | Boldine (50 mg/kg, p.o, for 7 days) attenuates Dextran Sulfate Sodium (DSS) -induced colitis in mice via p65-NF-κB and STAT3 signaling pathways[3].
| Animal Model: | DSS-induced mice model[3] | | Dosage: | 50 mg/kg | | Administration: | p.o. | | Result: | Reduced the expression of CD 68+ and activity of myeloperoxidase (MPO)
Attenuated Pro-Inflammatory Cytokines and the level of malondialdehyde (MDA)
Increased the Activities of Enzymic Antioxidants and Inhibited p65-NF-κB and STAT3 Activity.
|
|
| | Boldine Preparation Products And Raw materials |
|