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| | H-D-Pro-Phe-Arg-chloromethylketone Basic information |
| Product Name: | H-D-Pro-Phe-Arg-chloromethylketone | | Synonyms: | DPRO-PHE-ARG-CHLOROMETHYLKETONE;DPRO-PHE-ARG-CMK;H-D-Pro-Phe-Arg-chloromethylketone trifluoroacetate salt;H-D-Pro-Phe-Arg-CMK;L-Phenylalaninamide, D-prolyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-;pFR-CMK;H-D-Pro-Phe-Arg-chloromethylketone | | CAS: | 88546-74-1 | | MF: | C21H31ClN6O3 | | MW: | 450.96 | | EINECS: | | | Product Categories: | | | Mol File: | 88546-74-1.mol |  |
| | H-D-Pro-Phe-Arg-chloromethylketone Chemical Properties |
| density | 1.37±0.1 g/cm3(Predicted) | | storage temp. | -15°C | | pka | 13.01±0.46(Predicted) | | form | Solid | | color | White to off-white | | Sequence | {d-Pro}-Phe-{Arg-Chloromethylketone} |
| | H-D-Pro-Phe-Arg-chloromethylketone Usage And Synthesis |
| Uses | D-Pro-Phe-Arg-Chloromethylketone, a inhibitor of coagulation factor XII and plasma kallikrein, plays an important role in thrombosis and inflammation[1]. | | References | [1] Katrin F Nickel, et al. Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases. Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):13-20. DOI:10.1161/ATVBAHA.116.308595 |
| | H-D-Pro-Phe-Arg-chloromethylketone Preparation Products And Raw materials |
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