3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT

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3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT Basic information
Product Name:3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT
Synonyms:CORDYCEPIN 5'-TRIPHOSPHATE SODIUM SALT;3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT;cordycepin 5'-triphosphate sodium;3'-deoxyadenosine 5'-triphosphate;Cordycepin-5''-triphosphoric acid;3'-deoxyadenosine-5'-triphosphate sodium;Cordycepin 5′-triphosphate;Sodium (2R,3R,5S)-2-(6-amino-9H-purin-9-yl)-5-(((hydroxy((hydroxy(phosphonooxy)phosphoryl)oxy)phosphoryl)oxy)methyl)tetrahydrofuran-3-olate
CAS:71997-32-5
MF:C10H17N5NaO12P3
MW:515.18
EINECS:
Product Categories:
Mol File:71997-32-5.mol
3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT Structure
3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT Chemical Properties
storage temp. -20°C
form powder
InChIKeyFRGBONDYLMUOMH-UHFFFAOYSA-N
SMILES[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)CC3O
Safety Information
Hazard Codes Xn
Risk Statements 20/22-36/37/38-40
Safety Statements 22-26-36-45
WGK Germany 3
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
Carc. 2
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
ProviderLanguage
SigmaAldrich English
3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT Usage And Synthesis
UsesCordycepin 5′-triphosphate sodium salt has been used:
  • as a transcriptional inhibitor in RNA decay assay
  • to inhibit polyadenylation in HEK293T cells before harvesting for in- vitro interaction studies through co-immunoprecipitation (co-Ips)
  • as a positive control in in vitro assays for polymerase inhibition
  • as a precursor to produce cordycepin monophosphate

DefinitionChEBI: Cordycepin triphosphate is a purine ribonucleoside 5'-triphosphate. It has a role as an antimetabolite, an antifungal agent, an antineoplastic agent and an antiviral agent. It is functionally related to a cordycepin.
General DescriptionCordycepin (3′-deoxyadenosine) is a cytotoxic adenosine analog and a bioactive agent extracted from Cordyceps militaris. Cordycepin 5′-triphosphate is a toxic derivative of cordycepin.
Biochem/physiol ActionsCordycepin exhibits various metabolic effects by activating AMP-activated protein kinase (AMPK) in humans. Cordycepin triphosphate inhibits picornavirus polymerase-specific RNA synthesis by blocking in vitro [3H]GMP incorporation. It also retards cell growth by inhibiting RNA synthesis.
3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT Preparation Products And Raw materials
Tag:3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT(71997-32-5) Related Product Information
Adenosine5'-(tetrahydrogen triphosphate), disodiuM salt, trihydrate (9CI) L-Methionine,2'-ester with 3'-deoxyadenosine Cordycepin A[5']P5[5']A SODIUM SALT Adenosine triphosphate A[5']P5[5']A AMMONIUM SALT 2-METHYLTHIOADENOSINE TRIPHOSPHATE TETRASODIUM CAGED ATP, DISODIUM SALT A[5']P6[5']A AMMONIUM SALT DIADENOSINE TRIPHOSPHATE AMMONIUM SALT ADENOSINE 5'-TRIPHOSPHATE TRIS SALT 3'-DEOXYADENOSINE 5'-TRIPHOSPHATE SODIUM SALT 2'- AND 3'-O-(4-BENZOYLBENZOYL)-ADENOSINE 5'-TRIPHOSPHATE TRIETHYLAMMONIUM SALT adenosine 5'-tetraphosphate 8-BROMO-ADENOSINE-5'-TRIPHOSPHATE, SODIUM SALT A[5']P4[5']A AMMONIUM SALT P1,P5-Di(adenosine-5'-)pentaphosphate, trilithium salt P1,P5-Di(adenosine-5'-)pentaphosphate, trilithium salt