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| | (1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)- Basic information |
| Product Name: | (1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)- | | Synonyms: | 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-;Androst-4-ene-17-carbothioic acid;(6α,8ξ,11β,14ξ,16α,17α)-6,9-Difluoro-17-{[(fluoromethyl)sulfanyl] carbonyl}-11-hydroxy-16-methyl-3-oxoandrost-4-en-17-yl propionate;Fluticasone EP Imp E;Fluticasone Propionate EP Impurity E/1,2-Dihydro Fluticasone Propionate/6α,9-Difluoro-17-[[(fluoromethyl)sulphanyl]carbonyl]-11β-hydroxy-16α-methyl-3-oxoandrost-4-en-17α-yl propanoate;(6α,8ξ,11β,14ξ,16α,17α)-6,9-Difluoro-17-{[(fluoromethyl)sulfanyl] carbonyl}-11-hydroxy-16-methyl-3-oxoandrost-4-en-17-yl propionate
;Androst-4-ene-17-carbothioic acid, 6,9-difluoro-11-hydroxy- 16-Methyl-3-oxo-17-(1- oxopropoxy)-, S-(fluoroMethyl) ester, (6α,11β,16α,17α)-;Androst-4-ene-17-carbothioicacid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-,S-(fluoromethyl) ester, (6a,11b,16a,17a)- (9CI) | | CAS: | 105613-90-9 | | MF: | C25H33F3O5S | | MW: | 502.59 | | EINECS: | | | Product Categories: | | | Mol File: | 105613-90-9.mol |  |
| | (1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)- Chemical Properties |
| Melting point | 196-199°C (dec.) | | Boiling point | 567.9±50.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 12.62±0.70(Predicted) | | color | White to Light Brown | | Stability: | Hygroscopic | | Major Application | pharmaceutical |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2 Skin Sens. 1 |
| | (1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)- Usage And Synthesis |
| Uses | 1,2-Dihydro Fluticasone Propionate is an impurity of Fluticasone Propionate (F599500), a derivative of Flumethasone (F455000). An antiallergic; anti-asthmatic; anti-inflammatory. |
| | (1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)- Preparation Products And Raw materials |
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