STRESSCOPIN (3-40) (HUMAN) TRIFLUOROACETATE SALT

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STRESSCOPIN (3-40) (HUMAN) TRIFLUOROACETATE SALT Basic information
Product Name:STRESSCOPIN (3-40) (HUMAN) TRIFLUOROACETATE SALT
Synonyms:STRESSCOPIN (3-40) (HUMAN);STRESSCOPIN (3-40) (HUMAN) TRIFLUOROACETATE SALT;STRESSCOPIN TRIFLUOROACETATE SALT HUMAN;THR-LYS-PHE-THR-LEU-SER-LEU-ASP-VAL-PRO-THR-ASN-ILE-MET-ASN-LEU-LEU-PHE-ASN-ILE-ALA-LYS-ALA-LYS-ASN-LEU-ARG-ALA-GLN-ALA-ALA-ALA-ASN-ALA-HIS-LEU-MET-ALA-GLN-ILE-NH2 TRIFLUOROACETATE SALT;PHE-THR-LEU-SER-LEU-ASP-VAL-PRO-THR-ASN-ILE-MET-ASN-LEU-LEU-PHE-ASN-ILE-ALA-LYS-ALA-LYS-ASN-LEU-ARG-ALA-GLN-ALA-ALA-ALA-ASN-ALA-HIS-LEU-MET-ALA-GLN-ILE-NH2;UROCORTIN III HUMAN;UROCORTIN III (HUMAN) TRIFLUOROACETATE SALT;H-PHE-THR-LEU-SER-LEU-ASP-VAL-PRO-THR-ASN-ILE-MET-ASN-LEU-LEU-PHE-ASN-ILE-ALA-LYS-ALA-LYS-ASN-LEU-ARG-ALA-GLN-ALA-ALA-ALA-ASN-ALA-HIS-LEU-MET-ALA-GLN-ILE-NH2
CAS:357952-09-1
MF:C185H307N53O50S2
MW:4137.87218
EINECS:
Product Categories:Peptide;CRF;CRFPeptides for Cell Biology;Neuropeptides;Releasing Factors
Mol File:357952-09-1.mol
STRESSCOPIN (3-40) (HUMAN) TRIFLUOROACETATE SALT Structure
STRESSCOPIN (3-40) (HUMAN) TRIFLUOROACETATE SALT Chemical Properties
storage temp. −20°C
solubility H2O: soluble
form solid
SequencePhe-Thr-Leu-Ser-Leu-Asp-Val-Pro-Thr-Asn-Ile-Met-Asn-Leu-Leu-Phe-Asn-Ile-Ala-Lys-Ala-Lys-Asn-Leu-Arg-Ala-Gln-Ala-Ala-Ala-Asn-Ala-His-Leu-Met-Ala-Gln-Ile-NH2
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
STRESSCOPIN (3-40) (HUMAN) TRIFLUOROACETATE SALT Usage And Synthesis
UsesUrocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III (human) preferentially binds and activates CRF-R2 and has a discrete central nervous system and peripheral distribution. Urocortin III (human) selectively binds to type 2 CRF receptors with Ki values of 13.5, 21.7, and >100 nM for mCRF2β, rCRF2α, and hCRF1, respectively. Urocortin III (human) mediates somatostatin-dependent negative feedback control of Insulin (human) (HY-P0035) secretion[1][2].
References[1] Lewis K, et, al. Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7570-5. DOI:10.1073/pnas.121165198
[2] van der Meulen T, et, al. Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion. Nat Med. 2015 Jul;21(7):769-76. DOI:10.1038/nm.3872
STRESSCOPIN (3-40) (HUMAN) TRIFLUOROACETATE SALT Preparation Products And Raw materials
Tag:STRESSCOPIN (3-40) (HUMAN) TRIFLUOROACETATE SALT(357952-09-1) Related Product Information
FTLSLDVPTNIMNILFNIDKAKNLRAKAAANAQLMAQI-NH2 UROTENSIN II (HUMAN) urotensin II Uroguanylin Topoisomer B (human) Uroguanylin (human) UROTENSIN I UROCORTIN (RAT) STRESSCOPIN-RELATED PEPTIDE (6-43) (HUMAN) TRIFLUOROACETATE SALT UROCORTIN (HUMAN) UROTENSIN-II UROTENSIN II, RAT Urotensin II (Frog) ASP-PEN-PHE-TRP-LYS-TYR-CYS-VAL Urocortin II (mouse) Ethyl isocyanoacetate SALCOMINE METHYL ISOCYANOACETATE COBALT(II) ACETYLACETONATE