UROTENSIN II (HUMAN) manufacturers
- UROTENSIN II (HUMAN)
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- $7.00
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2020-02-17
- CAS: 251293-28-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100KG
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| | UROTENSIN II (HUMAN) Basic information |
| Product Name: | UROTENSIN II (HUMAN) | | Synonyms: | UROTENSIN II (HUMAN) HYDROCHLORIDE;UROTENSIN II (HUMAN);ETPDCFWKYCV, HCL (DISULFIDE BRIDGE: 5-10);GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL;GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL HYDROCHLORIDE;Urotensin II human, ≥97% (HPLC);H-GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH, HCL (DISULFIDE BRIDGE: 5-10);H-GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH | | CAS: | 251293-28-4 | | MF: | C64H85N13O18S2 | | MW: | 1388.57 | | EINECS: | | | Product Categories: | Peptide;Urotensin receptor | | Mol File: | 251293-28-4.mol |  |
| | UROTENSIN II (HUMAN) Chemical Properties |
| Boiling point | 1760.5±65.0 °C(Predicted) | | density | 1.46±0.1 g/cm3(Predicted) | | storage temp. | -15°C | | form | Solid | | pka | 3.60±0.10(Predicted) | | biological source | synthetic | | Water Solubility | Soluble to 1 mg/ml in water | | Sequence | Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val (Disulfide bridge: Cys5-Cys7) | | InChIKey | HFNHAPQMXICKCF-USJMABIRSA-N |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | UROTENSIN II (HUMAN) Usage And Synthesis |
| Uses | Urotensin II human was used in agonist and antagonist preparation for calcium mobilization assay. The product can also be used as a test compound for studying the impact of dihydropyridine calcium antagonist amlodipine in human internal mammary artery and clinical implications. | | Biochem/physiol Actions | Human urotensin II is a vasoactive neuropeptide that belongs to CRF family and stimulates arterial smooth muscle contraction, actin stress fiber formation and proliferation via small GTPase RhoA and there downstream effector Rho-kinase activation.The product is also a selective and potent vasoconstrictor agent as well as an agonist for the orphan receptor GPR14. | | in vivo | Human Urotensin II (U-II) markedly increases total peripheral resistance in anaesthetized non-human primates, a response associated with profound cardiac contractile dysfunction[1]. | | storage | Desiccate at -20°C |
| | UROTENSIN II (HUMAN) Preparation Products And Raw materials |
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