UROCORTIN (RAT) manufacturers
- UROCORTIN (RAT)
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- $1.00
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2020-03-06
- CAS:171543-83-2
- Min. Order: 1g
- Purity: ≥98%
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| | UROCORTIN (RAT) Basic information |
| | UROCORTIN (RAT) Chemical Properties |
| storage temp. | -20°C | | solubility | 1% acetic acid: >1 mg/mL, clear, colorless | | form | powder | | color | White to off-white | | biological source | rat | | Water Solubility | Soluble to 1 mg/ml in water | | Sequence | Asp-Asp-Pro-Pro-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2 |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | UROCORTIN (RAT) Usage And Synthesis |
| Uses | Urocortin rat can be used for western blotting. The product can also be used for studying that whether CRF receptor type 2 (CRF2) and its high-affinity ligand, urocortin 1 (Ucn1) can mediate sex-specific cellular stress responses by using corticotropin-releasing factor receptor 2-deficient (Crhr2-/- ) and wild-type (WT) mice. | | Biochem/physiol Actions | Urocortin is a CRF-related neuropeptide that binds to CRF receptor types 1α, 2α and 2β. It possesses appetite-suppressing effect. Urocortin along with corticotropin-releasing factor (CRF) binding protein (CRF-BP) enhances the free CRF levels in human brain by displacing hCRF from the binding protein. | | in vivo | Urocortin, rat (0.01 to 10 μg) decreases food intake in both food-deprived and non-deprived rats and such an effect also observed in mice after 1 μg of Urocortin, rat i.c.v. administration. Urocortin, rat has the potential of inducing anxiogenic behavior[3]. | | IC 50 | CRFR1; CRFR2 |
| | UROCORTIN (RAT) Preparation Products And Raw materials |
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