|
|
| | H-Met-Ser-OH Basic information |
| | H-Met-Ser-OH Chemical Properties |
| Boiling point | 548.6±50.0 °C(Predicted) | | density | 1.334±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | pka | 2.93±0.10(Predicted) | | CAS DataBase Reference | 14517-43-2 |
| | H-Met-Ser-OH Usage And Synthesis |
| Uses | Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension[1][2]. | | Definition | ChEBI: Met-Ser is a dipeptide composed of L-methionine and L-serine joined by a peptide linkage. It has a role as a metabolite. It is functionally related to a L-methionine and a L-serine. | | References | [1] Diana Hjmark Omkvist, et al. Affinity and translocation relationships via hPEPT1 of H-X aa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs. Eur J Pharm Biopharm. 2011 Feb;77(2):327-31. DOI:10.1016/j.ejpb.2010.12.009
[2] Pan Wuguang, et al. Application of sulfur dipeptide for preparing antihypertensive drug or health care product. Patent WO2019006954. |
| | H-Met-Ser-OH Preparation Products And Raw materials |
|