| Company Name: |
GL Biochem (Shanghai) Ltd
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| Tel: |
21-61263452 13641803416 |
| Email: |
ymbetter@glbiochem.com |
| Products Intro: |
Product Name:H-Met-Ser-OH CAS:14517-43-2 Purity:95% HPLC,98% HPLC Package:10mg, 25mg, 50mg, 100mg, 500mg, 1g,10g
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| | H-MET-SER-OH Basic information |
| | H-MET-SER-OH Chemical Properties |
| Boiling point | 548.6±50.0 °C(Predicted) | | density | 1.334±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | pka | 2.93±0.10(Predicted) | | CAS DataBase Reference | 14517-43-2 |
| | H-MET-SER-OH Usage And Synthesis |
| Uses | Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension[1][2]. | | Definition | ChEBI: Met-Ser is a dipeptide composed of L-methionine and L-serine joined by a peptide linkage. It has a role as a metabolite. It is functionally related to a L-methionine and a L-serine. | | References | [1] Diana Hjmark Omkvist, et al. Affinity and translocation relationships via hPEPT1 of H-X aa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs. Eur J Pharm Biopharm. 2011 Feb;77(2):327-31. DOI:10.1016/j.ejpb.2010.12.009 [2] Pan Wuguang, et al. Application of sulfur dipeptide for preparing antihypertensive drug or health care product. Patent WO2019006954. |
| | H-MET-SER-OH Preparation Products And Raw materials |
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