- MEGA-10
-
-
2026-09-11
- CAS:85261-20-7
- Min. Order: 1G
- Purity: 98%min
- Supply Ability: 30kg/month
|
| | MEGA-10 Basic information |
| Product Name: | MEGA-10 | | Synonyms: | N-Methyl-N-decanoylglucamine;N-Decanoyl-N-methyl-1-amino-1-deoxy-D-glucitol;|N|-Decanoyl-|N|-methylglucamine (MEGA-10);MEGA-10 50 mM solution;MEGA-10 solution;MEGA-10;N-DECANOYL-N-METHYLGLUCAMIDE;N-DECANOYL-N-METHYLGLUCAMINE | | CAS: | 85261-20-7 | | MF: | C17H35NO6 | | MW: | 349.46 | | EINECS: | 617-695-7 | | Product Categories: | | | Mol File: | 85261-20-7.mol |  |
| | MEGA-10 Chemical Properties |
| Melting point | 91-93 °C | | Boiling point | 595.8±50.0 °C(Predicted) | | density | 1.155±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | H2O: 10 mg/mL at 20 °C, clear, colorless | | pka | 13.44±0.20(Predicted) | | form | Solid | | color | White to Off-White | | Water Solubility | Soluble in methanol at 50mg/ml. Also soluble in water at 10mg/ml 20 °C | | BRN | 6974359 | | InChI | 1S/C17H35NO6/c1-3-4-5-6-7-8-9-10-15(22)18(2)11-13(20)16(23)17(24)14(21)12-19/h13-14,16-17,19-21,23-24H,3-12H2,1-2H3 | | InChIKey | UMWKZHPREXJQGR-UHFFFAOYSA-N | | SMILES | OCC(O)C(O)C(O)C(O)CN(C)C(CCCCCCCCC)=O | | EPA Substance Registry System | N-Oxodecyl meglumine (85261-20-7) |
| | MEGA-10 Usage And Synthesis |
| Uses | Non-ionic detergent for solubilizing membrane proteins | | Purification Methods | Possible impurities are decanoic acid and N-methylglycamine. The former is removed by grinding the solid with Et2O and then with pet ether and drying over P2O5. It is twice recrystallised from MeOH/Et2O by dissolving in the minimum volume of MeOH, adding Et2O and drying in a vacuum. To remove the glycamine, the solid (800mg) is dissolved in hot H2O (10mL) and set aside. Mega-10 crystallises as colourless needles. These are filtered off and dried in a vacuum to constant weight. It is a good non-ionic non-hygroscopic detergent with a critical micelle concentration (CMC) of 7.4mM (0.26%) in 0.1M Tris-HCl pH 7.4 at 25o. [Hildreth Biochem J 207 363 1982.] |
| | MEGA-10 Preparation Products And Raw materials |
|