- YKL-06-061
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- $30.00
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2026-07-27
- CAS:2172617-15-9
- Purity: 99.81%
- Supply Ability: 10g
- YKL 06-061
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-
2026-06-30
- CAS:2172617-15-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10000KGS
- YKL 06-061
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- $1.00
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2020-02-04
- CAS:2172617-15-9
- Min. Order: 1KG
- Purity: 98-99.9%
- Supply Ability: 100kg
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| | Ykl 06-061 Basic information |
| Product Name: | Ykl 06-061 | | Synonyms: | YKL-06-061; YKL06-061; YKL 06-061; YKL-06061; YKL06061; YKL 06061;Pyrimido[4,5-d]pyrimidin-2(1H)-one, 1-cyclobutyl-3-(2,6-dimethylphenyl)-3,4-dihydro-7-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-;YKL 06 061,Salt-inducible Kinase (SIK),inhibit,Inhibitor,YKL06061;YKL-06-061, 10 mM in DMSO;YKL 06-061 ，S0051;Ykl 06-061 | | CAS: | 2172617-15-9 | | MF: | C30H37N7O2 | | MW: | 527.66 | | EINECS: | | | Product Categories: | API | | Mol File: | 2172617-15-9.mol |  |
| | Ykl 06-061 Chemical Properties |
| Boiling point | 719.8±70.0 °C(Predicted) | | density | 1.268±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C, protect from light, stored under nitrogen | | solubility | DMSO: 62.5 mg/mL (118.45 mM); Water: < 0.1 mg/mL (insoluble) | | form | Solid | | pka | 7.76±0.42(Predicted) | | color | White to off-white |
| | Ykl 06-061 Usage And Synthesis |
| Uses | YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1]. | | IC 50 | SIK1 | | References | [1] Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184. DOI:10.1016/j.celrep.2017.05.042 |
| | Ykl 06-061 Preparation Products And Raw materials |
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