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| | (αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid Basic information |
| Product Name: | (αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid | | Synonyms: | 4-triazole-1-butanoic Acid;Isavuconazole interMediate 4;(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanoic acid;(alphaR,betaR)-beta-(2,5-Difluorophenyl)-beta-hydroxy-alpha-methyl-1H-1,2,4-triazole-1-butanoic Acid;1H-1,2,4-Triazole-1-butanoic acid, β-(2,5-difluorophenyl)-β-hydroxy-α-methyl-, (αR,βR)-;(αR;(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1;(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic Acid | | CAS: | 483340-19-8 | | MF: | C13H13F2N3O3 | | MW: | 297.26 | | EINECS: | | | Product Categories: | | | Mol File: | 483340-19-8.mol |  |
| | (αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid Chemical Properties |
| Melting point | 191-193 °C(Solv: methanol (67-56-1)) | | Boiling point | 519.9±60.0 °C(Predicted) | | density | 1.43±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DCM, Methanol | | pka | 3.89±0.23(Predicted) | | Appearance | White to off-white Solid | | Optical Rotation | -46.712° (C=1.0190 g/100ml, MEOH) |
| | (αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid Usage And Synthesis |
| Uses | (αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic Acid is an intermediate in the synthesis of Isavuconazole (I777830), an triazole based antifungal agent for the treatment of invasive fungal infections. |
| | (αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid Preparation Products And Raw materials |
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