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| | Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Basic information |
| Product Name: | Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- | | Synonyms: | Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)-;6,7-dimethoxy-4-(4-nitrophenoxy)-Quinoline;Cabozantinib Genotoxic Impurity II;6,7-dimethoxy-4-(4-nitrophenoxy)quinolineQ: What is
6,7-dimethoxy-4-(4-nitrophenoxy)quinoline Q: What is the CAS Number of
6,7-dimethoxy-4-(4-nitrophenoxy)quinoline;Cabozantinib Nitro Analog;6,7-dimethoxy-4-(4-nitrophenoxy)quinoline? (Cabozantinib Impurity）;Cabozantinib Impurity: 6,7-dimethoxy-4-(4-nitrophenoxy)-Quinoline | | CAS: | 190728-24-6 | | MF: | C17H14N2O5 | | MW: | 326.3 | | EINECS: | | | Product Categories: | | | Mol File: | 190728-24-6.mol |  |
| | Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Chemical Properties |
| Boiling point | 480.9±40.0 °C(Predicted) | | density | 1.319±0.06 g/cm3(Predicted) | | pka | 4.33±0.30(Predicted) | | InChI | InChI=1S/C17H14N2O5/c1-22-16-9-13-14(10-17(16)23-2)18-8-7-15(13)24-12-5-3-11(4-6-12)19(20)21/h3-10H,1-2H3 | | InChIKey | YRYKZXCOGVCXBN-UHFFFAOYSA-N | | SMILES | N1C2C(=CC(OC)=C(OC)C=2)C(OC2=CC=C([N+]([O-])=O)C=C2)=CC=1 |
| | Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Usage And Synthesis |
| Uses | 6,7-Dimethoxy-4-(4-nitrophenoxy)quinoline is a related compound of cabozantinib (CAS# 849217-68-1) with potential anticancer activity. It can be used in the preparation of nicotinamide derivatives as Aurora kinase inhibitors, nquinolinyloxyphenylbenzenesulfonamides as AXL kinase inhibitors, N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas as vascular endothelial growth factor receptor 2 (VEGFR-2) tyrosine kinase inhibitors, and phenoxyquinolines as specific inhibitors of platelet-derived growth factor receptor tyrosine kinase. |
| | Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- Preparation Products And Raw materials |
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