| Company Name: |
shlmai |
| Tel: |
021-67680335 13052188602 |
| Email: |
sale1@shlmai.net |
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| Product Name: | CLATP | | Synonyms: | ATPCL;ACLY;ATP Citrate Lyase Active human;ATP-citrate synthase;CLATP | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![CLATP Structure]() |
| | CLATP Chemical Properties |
| storage temp. | -70°C | | form | aqueous solution | | Specific Activity | ≥1.2pmol/min-μg |
| WGK Germany | WGK 2 | | Storage Class | 10 - Combustible liquids |
| | CLATP Usage And Synthesis |
| Uses | Active human ATP citrate lyase is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Active human ATP citrate lyase has been used in a study to ascertain the nature of the catalytic phosphorylation that initiates the ACL reaction, and to identity the active site residues involved. Active human ATP citrate lyase has also been used in a study to analyze tumor metabolism to reveal mitochondrial glucose oxidation in genetically diverse human glioblastomas. | | General Description | Human ATP citrate lyase (ACLY) (GenBank Accession No. NM_001096), full length, with N-terminal GST tag, MW = 147 kDa, expressed in baculovirus expression system. | | Biochem/physiol Actions | ATP citrate lyase is an enzyme involved in fatty acid synthesis that generates cytosolic acetyl-CoA and oxaloacetate from citrate and CoA. ATP citrate lyase is often upregulated in cancer. |
| | CLATP Preparation Products And Raw materials |
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