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| Product Name: | Cy7.5 | | Synonyms: | Cy7.5;sulfo Cy7.5(Et);sulfo Cy7.5;2-(7-(3-(5-Carboxypentyl)-1,1-dimethyl-6,8-disulfo-1,3-dihydro-2H-benzo[e]indol-2-ylidene)hepta-1,3,5-trien-1-yl)-3-ethyl-1,1-dimethyl-6-sulfo-1H-benzo[e]indol-3-ium-8-sulfonate;2-(7-(3-(5-carboxypentyl)-1,1-dimethyl-6,8-disulfo-1,3-dihydro-2H-benzo[e]indol-2-ylidene)hepta-1,3,5-trien-1-yl)-3-ethyl-1,1-dimethyl-8-sul;Sulfo-Cy7.5-E Free Acid (NIR);Diisopropyl-phosphoramidous acid (2S,3R,4R,5R)-5-[2,6-bis-(2-phenoxy-acetylamino)-purin-9-yl]-4-(tert-butyl-dimethyl-silanyloxy)-3-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-tetrahydro-furan-2-ylmethyl ester 2-cyano-ethyl ester;(2E)-2-[(2E,4E,6E)-7-[3-(5-carboxypentyl)-1,1-dimethyl-6,8-disulfobenzo[e]indol-3-ium-2-yl]hepta-2,4,6-trienylidene]-3-ethyl-1,1-dimethyl-6-sulfobenzo[e]indole-8-sulfonate | | CAS: | 847180-48-7 | | MF: | C43H46N2O14S4 | | MW: | 943.08 | | EINECS: | | | Product Categories: | | | Mol File: | 847180-48-7.mol |  |
| | Cy7.5 Chemical Properties |
| solubility | Easily soluble in methanol, DMF and other organic solvents, very soluble in water | | form | Solid | | color | Dark purple to black | | Appearance | Dark green solid | | ex/em | 778/797nm | | ε(extinction coefficient) | 222000 L⋅mol−1⋅cm−1 | | Φ(quantum yield) | 0.21 | | InChIKey | ISGPOTXIUFNEFH-UHFFFAOYSA-N | | SMILES | CC1(C(N(CCCCCC(=O)O)C2C=CC3=C(C=C(S(O)(=O)=O)C=C3C1=2)S(O)(=O)=O)=CC=CC=CC=CC1C(C2C3=CC(S(O)(=O)=O)=CC(S([O-])(=O)=O)=C3C=CC=2[N+]=1CC)(C)C)C |
| | Cy7.5 Usage And Synthesis |
| Chemical Properties | Appearance: Dark green solid
ex/em: 778/797nm
Extinction coefficient (ε): 222000 Lmol1cm1
Quantum yield (Φ): 0.21 | | Uses | Cy7.5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[2]. | | References | [1] Ptaszek M. Rational design of fluorophores for in vivo applications. Prog Mol Biol Transl Sci. 2013;113:59-108. DOI:10.1016/B978-0-12-386932-6.00003-X
[2] Zhan Y, et al. In Vivo Dual-Modality Fluorescence and Magnetic Resonance Imaging-Guided Lymph Node Mapping with Good Biocompatibility Manganese Oxide Nanoparticles. Molecules. 2017 Dec 12;22(12). pii: E2208. DOI:10.3390/molecules22122208
[3] Shindy, H. A. (2017). Fundamentals in the chemistry of cyanine dyes: A review. Dyes and Pigments, 145, 505–513. doi:10.1016/j.dyepig.2017.06.029 |
| | Cy7.5 Preparation Products And Raw materials |
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