| Company Name: |
TargetMol |
| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
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| | TGF-beta RI Kinase Inhibitor VII Basic information |
| Product Name: | TGF-beta RI Kinase Inhibitor VII | | Synonyms: | TGF-beta RI Kinase Inhibitor VII;1-(2-((6,7-Dimethoxyquinolin-4-yl)oxy)-4,5-dimethylphenyl)ethan-1-one;TGF-β RI Kinase Inhibitor VII;TGF-βRI inhibitor 3 | | CAS: | 666729-57-3 | | MF: | C21H21NO4 | | MW: | 351.39574 | | EINECS: | | | Product Categories: | | | Mol File: | 666729-57-3.mol |  |
| | TGF-beta RI Kinase Inhibitor VII Chemical Properties |
| | TGF-beta RI Kinase Inhibitor VII Usage And Synthesis |
| Uses | TGF-βRI inhibitor 3 (Compound 9ac) is a selective TGF-β inhibitor. TGF-βRI inhibitor 3 can effectively inhibit the TGF-β signaling pathway. TGF-βRI inhibitor 3 has IC50 values of 13 μM and 0.63 μM for c-Src kinase and ALK5 kinase, respectively[1]. | | References | [1] Shimizu T, et al. Synthesis and evaluation of [2-(4-quinolyloxy)phenyl]methanone derivatives: novel selective inhibitors of transforming growth factor-beta kinase. J Med Chem. 2008 Jun 12;51(11):3326-9. DOI:10.1021/jm701626z |
| | TGF-beta RI Kinase Inhibitor VII Preparation Products And Raw materials |
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