Bromo-PEG3-phosphonic acid

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Bromo-PEG3-phosphonic acid Basic information
Product Name:Bromo-PEG3-phosphonic acid
Synonyms:Bromo-PEG3-phosphonic acid;Bromo-PEG3-C2-phosphonic acid;Phosphonic acid, P-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethyl]-;(2-[2-[2-(2-Bromo-ethoxy)ethoxy]ethoxy]ethyl)phosphonic acid
CAS:1148026-99-6
MF:C8H18BrO6P
MW:321.1
EINECS:
Product Categories:
Mol File:1148026-99-6.mol
Bromo-PEG3-phosphonic acid Structure
Bromo-PEG3-phosphonic acid Chemical Properties
Boiling point 458.1±55.0 °C(Predicted)
density 1.514±0.06 g/cm3(Predicted)
pka2.14±0.10(Predicted)
Safety Information
MSDS Information
Bromo-PEG3-phosphonic acid Usage And Synthesis
DescriptionBromo-PEG3-phosphonic acid is a PEG linker with bromine and phosphonic acid moieties. The bromine is a good leaving group. The hydrophilic PEG chain increases compound solubility in aqueous media.
UsesBromo-PEG3-C2-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG3-phosphonic acid Preparation Products And Raw materials
Tag:Bromo-PEG3-phosphonic acid(1148026-99-6) Related Product Information
Bromo-PEG4-t-butyl ester Bromo-PEG2-acid Ethanol, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1-methanesulfonate Bromo-PEG4-acid Bromo-PEG5-phosphonic acid ethyl ester Broxuridine Br-PEG3-MS 2H-Pyran, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]tetrahydro- Bromo-PEG5-phosphonic acid Br-PEG6-acid 2H-Pyran, 2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]tetrahydro- Bromo-PEG3-phosphonic acid ethyl ester Br-PEG5-NHBoc Br-PEG1-COOtBu Br-PEG6-THP Methanesulfonic acid 2-bromoethyl ester