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T&W GROUP |
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021-61551611 13296011611 |
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Bromo-PEG4-acid manufacturers
- Br-PEG4-acid
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2025-06-07
- CAS:1393330-38-5
- Min. Order: 5g
- Purity: >98.00%
- Supply Ability: 5g
- Bromo-PEG4-acid
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- $1.00
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2019-12-23
- CAS:1393330-38-5
- Min. Order: 1KG
- Purity: 97%-99.9%
- Supply Ability: 100kg
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| | Bromo-PEG4-acid Basic information |
| Product Name: | Bromo-PEG4-acid | | Synonyms: | Bromo-PEG4-acid;Bromo-PEG5-acid;Br-PEG4-acid;Bromo-PEG4-propionic acid;Br-PEG4-CH2CH2COOH;CAS_1393330-38-5;Propanoic acid, 3-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]-;1-Bromo-3,6,9,12-tetraoxapentadecan-15-oic acid | | CAS: | 1393330-38-5 | | MF: | C11H21BrO6 | | MW: | 329.18 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1393330-38-5.mol |  |
| | Bromo-PEG4-acid Chemical Properties |
| Boiling point | 426.9±40.0 °C(Predicted) | | density | 1.352±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Soluble in Water, DMSO, DMF, DCM | | pka | 4.28±0.10(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | Bromo-PEG4-acid Usage And Synthesis |
| Description | Bromo-PEG4-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | | Uses | Bromo-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Bromo-PEG4-acid Preparation Products And Raw materials |
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