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| | m-PEG3-NHS carbonate Basic information |
| Product Name: | m-PEG3-NHS carbonate | | Synonyms: | m-PEG3-NHS carbonate;m-PEG3-succinimidyl carbonate;Meo-dpego-co-nhs;N-Hydroxysuccinimide MeO-Peg3 carbonate;2,5-Pyrrolidinedione, 1-[(1-oxo-2,5,8,11-tetraoxadodec-1-yl)oxy]-;2,5,8,11-Tetraoxadodecanoic acid, 2,5-dioxo-1-pyrrolidinyl ester;mPEG3-SC;2,5-dioxopyrrolidin-1-yl (2-(2-(2-methoxyethoxy)ethoxy)ethyl) carbonate | | CAS: | 477775-77-2 | | MF: | C12H19NO8 | | MW: | 305.28 | | EINECS: | | | Product Categories: | | | Mol File: | 477775-77-2.mol |  |
| | m-PEG3-NHS carbonate Chemical Properties |
| | m-PEG3-NHS carbonate Usage And Synthesis |
| Description | m-PEG3-succinimidyl carbonate is a PEG linker containing a succinimidyl carbonate end group. The succinimidyl is amine reactive, forming stable amide bonds. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. | | Uses | m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] Miller MA, et al. Amphiphilic conjugates of human brain natriuretic peptide designed for oral delivery: in vitro activity screening. Bioconjug Chem. 2006 Mar-Apr;17(2):267-74. DOI:10.1021/bc0501000 |
| | m-PEG3-NHS carbonate Preparation Products And Raw materials |
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