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| | NPC-15437 dihydrochloride Basic information |
| Product Name: | NPC-15437 dihydrochloride | | Synonyms: | S-2,6-DIAMINO-N-([1-(1-OXOTRIDECYL)-2-PIPERIDINYL]METHYL)HEXANAMIDE DIHYDROCHLORIDE;S-2,6-DIAMINO-N-[[1'-(1''OXOTRIDECYL)-2'-PIPERIDINYL]METHYL]HEXANAMIDE DIHYDROCHLORIDE;S-2,6-DIAMINO-N-[[1'-(1'-OXOTRIDECYL)-2'-PIPERIDINYL]METHYL]HEXANAMIDE DIHYDROCHLORIDE;NPC-15437;(2S)-2,6-DIAMINO-N-[[1-(1-OXOTRIDECYL)-2-PIPERIDINYL]METHYL]HEXANAMIDE DIHYDROCHLORIDE;NPC154372HCl;Npc1537 dihydrochloride;Hexanamide, 2,6-diamino-N-[[1-(1-oxotridecyl)-2-piperidinyl]methyl]-, (2S)- | | CAS: | 136449-85-9 | | MF: | C25H50N4O2 | | MW: | 438.69 | | EINECS: | | | Product Categories: | Protein Kinase | | Mol File: | 136449-85-9.mol |  |
| | NPC-15437 dihydrochloride Chemical Properties |
| Boiling point | 641.557±45.00 °C(Press: 760.00 Torr)(predicted) | | density | 0.988±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | 2-8°C | | solubility | H2O: ≥36 mg/mL | | form | solid | | pka | 15.375±0.46(predicted) | | color | white |
| | NPC-15437 dihydrochloride Usage And Synthesis |
| Biological Activity | Highly selective, competitive and reversible inhibitor of protein kinase C (IC 50 = 19 mM); interacts at the regulatory domain of the enzyme. May modulate P-glycoprotein in tumor cells in vitro via inhibiton of PKC. Centrally active following systemic administration in vivo . | | storage | +4°C |
| | NPC-15437 dihydrochloride Preparation Products And Raw materials |
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