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| | 2-PIPERIDYLMETHYLAMINE Basic information |
| | 2-PIPERIDYLMETHYLAMINE Chemical Properties |
| Boiling point | 63-66°C/12mm | | density | 0.9406 g/mL at 25 °C | | refractive index | 1.4850 | | Fp | 63-66°C/12mm | | storage temp. | -20°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | | pka | 10.32±0.29(Predicted) | | color | Clear Colorless | | BRN | 102994 | | InChI | InChI=1S/C6H14N2/c7-5-6-3-1-2-4-8-6/h6,8H,1-5,7H2 | | InChIKey | RHPBLLCTOLJFPH-UHFFFAOYSA-N | | SMILES | N1CCCCC1CN | | CAS DataBase Reference | 22990-77-8(CAS DataBase Reference) |
| Hazard Codes | C | | Risk Statements | 34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | 2735 | | WGK Germany | 2 | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29333990 | | Storage Class | 8A - Combustible corrosive hazardous materials | | Hazard Classifications | Skin Corr. 1B |
| | 2-PIPERIDYLMETHYLAMINE Usage And Synthesis |
| Uses | 2-Piperidinemethanamine is used in the synthesis of compounds exhibiting anti-osteoclast and anti-osteoblast activity. It also is used in the synthesis of potent antibacterial. | | Uses | Reactant for reversible aminal formation
Reactant for synthesis of:
- Annulated N-heterocyclic carbene ligands
- M3 Muscarinic receptor antagonists
- Selective 5-ht5A receptor antagonists
- Ternary platinum(II) complexes
| | Purification Methods | Dry (over Na2SO4) and distil the piperidine under vacuum from KOH. It has been purified via the Reinekate salt (m 173-174o) and its dipicrate salt (m 201o, from H2O). [Norton et al. J Am Chem Soc 68 1330 1946, Mortimer Aust J Chem 11 84 1958, Augustine J Am Chem Soc 81 4667 1959, Beilstein 22 III/IV 3765.] |
| | 2-PIPERIDYLMETHYLAMINE Preparation Products And Raw materials |
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