13,14-Dihydro prostaglandin f2alpha manufacturers
|
| | 13,14-Dihydro prostaglandin f2alpha Basic information |
| Product Name: | 13,14-Dihydro prostaglandin f2alpha | | Synonyms: | (5Z,15S)-9α,11α,15-Trihydroxyprosta-5-ene-1-oic acid;13,14-dihydrodinoprost;13,14-dihydro-pgf2-alpha;7-(3,5-dihydroxy-2-(3-hydroxyoctyl)cyclopentyl)-5-heptenoicaci;7-(3,5-dihydroxy-2-(3-hydroxyoctyl)cyclopentyl)-5-heptenoicacid;(E)-7-[3,5-dihydroxy-2-(3-hydroxyoctyl)cyclopentyl]hept-5-enoic acid;LLQBSJQTCKVWTD-NFUXFLSFSA-N;(5Z,9α,11α,15S)-9,11,15-Trihydroxyprosta-5-ene-1-oic acid | | CAS: | 27376-74-5 | | MF: | C20H36O5 | | MW: | 356.5 | | EINECS: | | | Product Categories: | | | Mol File: | 27376-74-5.mol |  |
| | 13,14-Dihydro prostaglandin f2alpha Chemical Properties |
| storage temp. | Store at -20°C | | solubility | 10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a) |
| | 13,14-Dihydro prostaglandin f2alpha Usage And Synthesis |
| Description | 13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value for 13,14-dihydro PGF2α as a luteolytic agent in hamsters is 1.5 μg/100 g. | | Uses | 13,14-Dihydro-PGF2α is an analog of PGF2α which has no unsaturation in the lower side chain. It facilitates luteolysis in hamsters/rabbits with potency five times higher than PGF2α. | | Definition | ChEBI: A prostaglandins Falpha that is prost-5-en-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15. | | References | [1] NIELS H. ANDERSEN. Molecular basis for prostaglandin potency. III. Tests of the significance of the “hairpin conformation” in biorecognition phenomena[J]. Prostaglandins, 1981, 22 5: Pages 841-856. DOI: 10.1016/0090-6980(81)90222-7 |
| | 13,14-Dihydro prostaglandin f2alpha Preparation Products And Raw materials |
|