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| | 3,4-Dihydroxybenzylamine hydrobromide Basic information |
| Product Name: | 3,4-Dihydroxybenzylamine hydrobromide | | Synonyms: | 4-(AMINOMETHYL)CATECHOL HYDROBROMIDE;DHBA HYDROBROMIDE;4-(aminomethyl)pyrocatechol hydrobromide;3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDE, 9 8%;4-(Aminomethyl)catechol hydrobromide, DHBA hydrobromide;3,4-Dihydroxybenzylamine·hydrogen bromide;4-(Aminomethyl)pyrocatechol·hydrobrominate;3,4-Dihydroxybenzylamine hydrobromide,4-(Aminomethyl)catechol hydrobromide, DHBA hydrobromide | | CAS: | 16290-26-9 | | MF: | C7H10BrNO2 | | MW: | 220.06 | | EINECS: | 240-382-8 | | Product Categories: | Anilines, Aromatic Amines and Nitro Compounds | | Mol File: | 16290-26-9.mol |  |
| | 3,4-Dihydroxybenzylamine hydrobromide Chemical Properties |
| Melting point | 184-186 °C(lit.) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO (Slightly), Methanol (Very Slightly) | | form | Crystalline Powder | | color | Light beige | | Sensitive | Hygroscopic | | BRN | 4002646 | | InChI | 1S/C7H9NO2.BrH/c8-4-5-1-2-6(9)7(10)3-5;/h1-3,9-10H,4,8H2;1H | | InChIKey | BVFZTXFCZAXSHN-UHFFFAOYSA-N | | SMILES | Br.NCc1ccc(O)c(O)c1 | | CAS DataBase Reference | 16290-26-9(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | F | 10 | | HS Code | 29222900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| | 3,4-Dihydroxybenzylamine hydrobromide Usage And Synthesis |
| Chemical Properties | light beige crystalline powder | | Uses | 4-(Aminomethyl)benzene-1,2-diol hydrobromide is a useful reactant for the synthesis of capsaicin soft drugs. which are used to target the transient receptor potential vanilloid 1 channel (TRPV1). | | in vivo | 3,4-Dihydroxybenzylamine hydrobromide (intraperitoneal injection; 1000 mg/kg; 7 days) has the least toxic effect in non-tumor-bearing B6D2F1 mice,and mice is tolerated at this dose[3].
3,4-Dihydroxybenzylamine hydrobromide (intraperitoneal injection; 200-800 mg/kg; 21 days) has different effects at different doses, the median life-span are 17, 24.5, 26, 29 and 25 days for 0 mg/kg, 200 mg/kg, 400 mg/kg, 600 mg/kg, and 800 mg/kg, respectively[3]. | Animal Model: | C57BL/6 mice with B6D2F1 cells[3] | | Dosage: | 200 mg/kg, 400 mg/kg, 600 mg/kg, and 800 mg/kg | | Administration: | Intraperitoneal injection | | Result: | Exhibited increased life-span of 44%,46%, 70% and 50% for 200 mg/kg, 400 mg/kg, 600 mg/kg, and 800 mg/kg, respectively. |
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| | 3,4-Dihydroxybenzylamine hydrobromide Preparation Products And Raw materials |
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