|
|
| | 7-(2,4-dinitrophenoxy)-4-methylchromen-2-one Basic information |
| Product Name: | 7-(2,4-dinitrophenoxy)-4-methylchromen-2-one | | Synonyms: | 7-(2,4-dinitrophenoxy)-4-methylchromen-2-one;7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one;2H-1-Benzopyran-2-one, 7-(2,4-dinitrophenoxy)-4-methyl-;7-(2,4-dinitrophenoxy)-4-methyl-2H-1-benzopyran-2-one | | CAS: | 314742-00-2 | | MF: | C16H10N2O7 | | MW: | 342.26 | | EINECS: | | | Product Categories: | | | Mol File: | 314742-00-2.mol |  |
| | 7-(2,4-dinitrophenoxy)-4-methylchromen-2-one Chemical Properties |
| Boiling point | 496.4±45.0 °C(Predicted) | | density | 1.492±0.06 g/cm3(Predicted) | | solubility | Chloroform: 30mg/mL; DMF: 30mg/mL; DMF:PBS (pH 7.2) (1:2): 0.30mg/mL; DMSO: 5mg/mL | | form | A crystalline solid |
| | 7-(2,4-dinitrophenoxy)-4-methylchromen-2-one Usage And Synthesis |
| Uses | 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one (Compound 1) is a fluorescent probe for the detection of hydrogen sulfide (H2S). 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one has a low detection limit (4×10-6 mol/L), good selectivity and high sensitivity. 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one shows almost no cytotoxicity at concentrations of 150 μg/mL. 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one has the excitation peak of 331 nm, and the emission peak about 385 nm in DMSO solvent. Upon the addition of increasing amounts of HS-, the fluorescence intensity increases obviously at about 392 nm[1]. | | References | [1] Chen Y, et al. The synthesis, crystal, hydrogen sulfide detection and cell assement of novel chemsensors based on coumarin derivatives. Sci Rep. 2018 Nov 1;8(1):16159. DOI:10.1038/s41598-018-34331-9 |
| | 7-(2,4-dinitrophenoxy)-4-methylchromen-2-one Preparation Products And Raw materials |
|