- Ofurace
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- $1980.00
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2026-05-11
- CAS:58810-48-3
- Purity:
- Supply Ability: 10g
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| | Ofurace Basic information |
| | Ofurace Chemical Properties |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 36 | | WGK Germany | 2 | | RTECS | AE1300200 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2 |
| | Ofurace Usage And Synthesis |
| Uses | Ofurace is a systematic fungicide used to control diseases caused by phycomycetes. Ofurace is commonly used in agriculture to control potato late blight. | | Definition | ChEBI: 2-chloro-N-(2,6-dimethylphenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamide is an aromatic amide that is 2,6-dimethylaniline in which the two amino hydrogens are replaced by chloroacetyl and 2-oxotetrahydrofuran-3-yl groups It is an aromatic amide, an organochlorine compound, a butan-4-olide and a tertiary carboxamide. | | Production Methods | The commercial synthesis of ofurace involves constructing its core structure through acylation and lactone coupling reactions. The process begins with 2,6-dimethylaniline, which undergoes chloroacetylation using chloroacetyl chloride to form 2-chloro-N-(2,6-dimethylphenyl)acetamide. This intermediate is then reacted with tetrahydro-2-oxo-3-furanol, a γ-butyrolactone derivative, under controlled conditions to yield the final compound: Ofurace. The reaction typically takes place in an organic solvent like toluene or acetonitrile, with a base such as triethylamine to facilitate nucleophilic substitution. | | Mechanism of action | Systemic with curative and protective action. Disrupts fungal nucleic acid synthesis - RNA ploymerase 1. | | Pesticide Type | Fungicide |
| | Ofurace Preparation Products And Raw materials |
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