| Company Name: |
Absin Bioscience Inc.
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| Tel: |
021-38015121 18438616290 |
| Email: |
lanwu@univ-bio.com |
| Products Intro: |
Product Name:CHD3 antibody
Package:50ul Remarks: 见爱必信官网
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| Company Name: |
Hubei Serenity BioSolutions Co., Ltd.
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| Tel: |
027-19371278702 18008634902 |
| Email: |
19384116026@163.com |
| Products Intro: |
Product Name:Rabbit Polyclonal CHD3 Antibody
Package:20μl;50μl;100μl
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| Company Name: |
GeneTex, Inc.
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| Tel: |
0755-26755892 1-949-553-1900 |
| Email: |
international@genetex.com |
| Products Intro: |
Product Name:CHD3 antibody
|
| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Email: |
Enzoname@qq.com |
| Products Intro: |
Product Name:CHD3 Antibody
|
| Company Name: |
Biosynth Ltd
|
| Tel: |
18886812933 |
| Email: |
sales@biosynth.com |
| Products Intro: |
Product Name:CHD3 antibody
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| | CHD3 ANTIBODY Chemical Properties |
| | CHD3 ANTIBODY Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Mouse;Monkey | | Background | Chromodomain-helicase-DNA-binding domain proteins have been identified in a variety of organisms. This family of nine proteins is divided into three separate subfamilies: subfamily I, subfamily II, and subfamily III. All CHD proteins contain two tandem amino-terminal chromodomains, a SWI/SNF-related ATPase domain, and a carboxy-terminal DNA-binding domain. The chromodomains facilitate binding to methylated lysine residues of histone proteins and confer interactions with specific regions of chromatin. The SWI/SNF-related ATPase domain utilizes energy from ATP hydrolysis to modify chromatin structure. CHD proteins are often found in large, multiprotein complexes with their transcriptional activation or repression activity governed by other proteins within the complex. CHD3 and CHD4 are central components of the nucleosome remodeling and histone deacetylase transcriptional repressor complex, which also contains HDAC1, HDAC2, RBAP48, RBAP46, MTA1, MTA2, MTA3, and MBD3. Both CHD3 and CHD4 contain two plant homeodomain zinc finger domains that bind directly to HDAC1 and HDAC2. | | References | [1] Hall, J.A. and Georgel, P.T. (2007) Biochem Cell Biol 85, 463-76.
[2] Marfella, C.G. and Imbalzano, A.N. (2007) Mutat Res 618, 30-40.
[3] Tong, J.K. et al. (1998) Nature 395, 917-21.
[4] Xue, Y. et al. (1998) Mol Cell 2, 851-61.
[5] Zhang, Y. et al. (1998) Cell 95, 279-89.
[6] Bowen, N.J. et al. (2004) Biochim Biophys Acta 1677, 52-7.
[7] Jones, P.L. et al. (1998) Nat Genet 19, 187-91.
[8] Fujita, N. et al. (2003) Cell 113, 207-19. |
| | CHD3 ANTIBODY Preparation Products And Raw materials |
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