| Company Name: |
Chengdu Peter-like Biotechnology Co., Ltd. Gold
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| Tel: |
028-81700200 13308200041 |
| Email: |
2851167782@qq.com |
| Products Intro: |
Product Name:Lobetyolin
CAS:129277-38-9
Purity:HPLC>=98% 现货 Package:5mg10mg20mg50mg100mg500mg1g2g等应客户需求包装
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| Company Name: |
Chengdu Push Bio-Technology Co., Ltd. Gold
|
| Tel: |
028-85370565-229 18080489829 |
| Email: |
18080489829@163.com |
| Products Intro: |
Product Name:Lobetyolin
CAS:129277-38-9
Purity:98.0%(HPLC&TLC) Package:25mg/RMB 750
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| | Lobetyolin Basic information |
| Product Name: | Lobetyolin | | Synonyms: | β-D-Glucopyranoside, (1R,2R,7E)-2-hydroxy-1-[(1E)-5-hydroxy-1-pentenyl]-7-nonene-3,5-diynyl (9CI) | | CAS: | 129277-38-9 | | MF: | C20H28O8 | | MW: | 396.43 | | EINECS: | | | Product Categories: | | | Mol File: | 129277-38-9.mol |  |
| | Lobetyolin Chemical Properties |
| Boiling point | 698.5±55.0 °C(Predicted) | | density | 1.35±0.1 g/cm3(Predicted) | | pka | 11.39±0.20(Predicted) | | form | Solid | | color | White to yellow | | InChIKey | MMMUDYVKKPDZHS-FHMAEMBXNA-N | | SMILES | O([C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@]([H])(/C=C/CCCO)[C@H](O)C#CC#C/C=C/C |&1:1,2,3,5,7,12,20,r| |
| | Lobetyolin Usage And Synthesis |
| Uses | Lobetyolin, a bioactive compound, is derived from Codonopsis pilosula. Lobetyolin has anti-inflammatory, anti-oxidative and xanthine oxidase inhibiting activities. Lobetyolin also induces the apoptosis via the inhibition of ASCT2-mediated glutamine metabolism[1][2]. Lobetyolin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | References | [1] Yoon YP, et al. Effects of Lobetyolin, Lobetyol and Methyl linoleate on Secretion, Production and Gene Expression of MUC5AC Mucin from Airway Epithelial Cells. Tuberc Respir Dis (Seoul). 2014 Nov;77(5):203-8. DOI:10.4046/trd.2014.77.5.203
[2] He W, et, al. Lobetyolin induces apoptosis of colon cancer cells by inhibiting glutamine metabolism. J Cell Mol Med. 2020 Mar;24(6):3359-3369. DOI:10.1111/jcmm.15009 |
| | Lobetyolin Preparation Products And Raw materials |
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