| Company Name: |
Lynnchem |
| Tel: |
86-(0)29-85992781 17792393971 |
| Email: |
info@lynnchem.com |
| Company Name: |
Novachemistry |
| Tel: |
44-20819178-90 02081917890 |
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info@novachemistry.com |
- Kendomycin
-
- $889.00
-
2026-07-27
- CAS:183202-73-5
- Purity:
- Supply Ability: 10g
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| | KENDOMYCIN Basic information |
| Product Name: | KENDOMYCIN | | Synonyms: | kendomycin from streptomyces violaceoruber;1,19:5,9-Diepoxybenzocyclooctadecen-3(5H)-one, 6,7,8,9,10,11,12,15,16,17,18,19-dodecahydro-4,7,19-trihydroxy-2,6,8,12,14,16,18-heptamethyl-, (5R,6R,7S,8R,9R,12S,13E,16S,18S,19S)- | | CAS: | 183202-73-5 | | MF: | C29H42O6 | | MW: | 486.64 | | EINECS: | | | Product Categories: | | | Mol File: | 183202-73-5.mol |  |
| | KENDOMYCIN Chemical Properties |
| Melting point | 236-240℃ | | Boiling point | 678.5±55.0 °C(Predicted) | | density | 1.19±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | Soluble in DMSO | | form | solid | | pka | 8.53±0.70(Predicted) | | color | Yellow |
| | KENDOMYCIN Usage And Synthesis |
| Description | Kendomycin is a macrolide from Streptomyces which displays potent cytotoxicity against several carcinoma cell lines (GI50 < 100 nM). It also acts as an endothelin receptor antagonist and has antiosteoporotic activities. Certain effects are thought to be mediated through inhibition of proteasomal degradation of proteins. | | Uses | Kendomycin is an unusual macrocyclic metabolite containing a rare quinone methide group. Kendomycin is a potent antibacterial agent against Gram positive and Gram negative bacteria, including MRSA strains, also displaying antitumour activity. Kendomycin is a potent endothelin receptor agonist and demonstrates antiosteoporotic activity. | | Uses | Kendomycin is a broadly efficacious polyketide macrocycle antibiotic. | | Definition | ChEBI: Kendomycin is a member of benzofurans. | | storage | +4°C | | References | [1] KEVIN B. BAHNCK Scott D R. Formal Synthesis of ()-Kendomycin Featuring a Prins-Cyclization To Construct the Macrocycle[J]. Journal of the American Chemical Society, 2008, 130 39: 13177-13181. DOI: 10.1021/ja805187p |
| | KENDOMYCIN Preparation Products And Raw materials |
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