Benzoic acid, 2-fluoro-, 2-(2-naphthalenylsulfonyl)hydrazide

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Benzoic acid, 2-fluoro-, 2-(2-naphthalenylsulfonyl)hydrazide Basic information
Product Name:Benzoic acid, 2-fluoro-, 2-(2-naphthalenylsulfonyl)hydrazide
Synonyms:Benzoic acid, 2-fluoro-, 2-(2-naphthalenylsulfonyl)hydrazide;CTX-0124143;N'-(2-Naphthalenylsulfonyl)-2-fluoro-benzoic acid hydrazide;2-Fluoro-N'-naphthalen-2-ylsulfonylbenzohydrazide
CAS:423731-64-0
MF:C17H13FN2O3S
MW:344.36
EINECS:
Product Categories:
Mol File:423731-64-0.mol
Benzoic acid, 2-fluoro-, 2-(2-naphthalenylsulfonyl)hydrazide Structure
Benzoic acid, 2-fluoro-, 2-(2-naphthalenylsulfonyl)hydrazide Chemical Properties
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
Benzoic acid, 2-fluoro-, 2-(2-naphthalenylsulfonyl)hydrazide Usage And Synthesis
DescriptionCTX-012414 is a KAT6A inhibitor with IC50 value of 0.49 μM and KD value of 0.38 -M.
UsesCTX-0124143 is a KAT6A inhibitor with a sulfonyl hydrazine skeleton[1].
References[1] Duan Y, et al. Discovery of N-(2-oxoethyl) sulfanilamide-derived inhibitors of KAT6A (MOZ) against leukemia by an isostere strategy. Eur J Med Chem. 2023 Nov 15;260:115770. DOI:10.1016/j.ejmech.2023.115770
Benzoic acid, 2-fluoro-, 2-(2-naphthalenylsulfonyl)hydrazide Preparation Products And Raw materials
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