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4-Pregnen-6-beta, 17,21-triol-3,11,20-trione

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4-Pregnen-6-beta, 17,21-triol-3,11,20-trione Basic information
Product Name:4-Pregnen-6-beta, 17,21-triol-3,11,20-trione
Synonyms:4-PREGNEN-6BETA,17ALPHA,21-TRIOL-3,11,20-TRIONE;4-PREGNENE-6-BETA,17-ALPHA,21-TRIOL-3,11,20-TRIONE;6-BETA,17-ALPHA,21-TRIHYDROXY-4-PREGNENE-3,11,20-TRIONE;6-BETA-HYDROXYCORTISONE;NSC15457;4-Pregnene-6β,17α,21-triol-3,11,20-trione;6β-Hydroxycortisone;6β,17,21-Trihydroxypregna-4-ene-3,11,20-trione
CAS:16355-28-5
MF:C21H28O6
MW:376.44
EINECS:
Product Categories:
Mol File:16355-28-5.mol
4-Pregnen-6-beta, 17,21-triol-3,11,20-trione Structure
4-Pregnen-6-beta, 17,21-triol-3,11,20-trione Chemical Properties
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
4-Pregnen-6-beta, 17,21-triol-3,11,20-trione Usage And Synthesis
Uses6β-Hydroxycortisone-d7 is the isotope labelled analog of 6β-Hydroxycortisone (H918450); a compound that can be used as a probe to detect inhibition of CYP3A4 in vivo.
DefinitionChEBI: 6beta-hydroxycortisone is a C21-steroid that is cortisone bearing an additional hydroxy substituent at the 6beta-position. It is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. It has a role as a probe and a human metabolite. It is a C21-steroid, a 6beta-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 21-hydroxy steroid, a 20-oxo steroid, a 17alpha-hydroxy steroid, an 11-oxo steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It is functionally related to a cortisone.
4-Pregnen-6-beta, 17,21-triol-3,11,20-trione Preparation Products And Raw materials
Tag:4-Pregnen-6-beta, 17,21-triol-3,11,20-trione(16355-28-5) Related Product Information
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