- Cortexolone
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2026-09-20
- CAS:152-58-9
- Min. Order: 10kg
- Purity: 99.5%
- Supply Ability: 1000kg
- CORTEXOLONE
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- $50.00
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2026-09-02
- CAS:152-58-9
- Min. Order: 1KG
- Purity: 99%
- Cortodoxone
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- $44.00
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2026-07-27
- CAS:152-58-9
- Purity: 99.82%
- Supply Ability: 10g
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| | CORTEXOLONE Basic information |
| Product Name: | CORTEXOLONE | | Synonyms: | (8R,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one;Hydrocortisone Impurity 6（Hydrocortisone EP Impurity F）;11-DEOXYCORTISOL; CORTEXOLONE; REICHSTEIN'S SUBSTANCE S;11-dioxy-cortiso;11-dioxycortisol;17,21-dihydroxy-pregn-4-ene-20-dione;17-hydroxy-11-deoxycorticosterone;nsc-18317 | | CAS: | 152-58-9 | | MF: | C21H30O4 | | MW: | 346.46 | | EINECS: | 205-805-2 | | Product Categories: | Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Biochemistry;Hydroxyketosteroids;Pharmaceutical Raw Materials;152-58-9;1 | | Mol File: | 152-58-9.mol |  |
| | CORTEXOLONE Chemical Properties |
| Melting point | 205-208 °C | | Boiling point | 401.19°C (rough estimate) | | density | 1.22±0.1 g/cm3 (20 ºC 760 Torr) | | refractive index | 120 ° (C=1, Dioxane) | | Fp | 9℃ | | storage temp. | Sealed in dry,Room Temperature | | solubility | Dioxane (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly, Heated) | | form | Solid | | pka | 12+-.0.60(Predicted) | | color | White to Off-White | | Water Solubility | 44.08mg/L(37 ºC) | | Merck | 14,2932 | | Major Application | diagnostic assay manufacturing
hematology
histology | | InChI | InChI=1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1 | | InChIKey | WHBHBVVOGNECLV-OBQKJFGGSA-N | | SMILES | C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)[C@@](O)(C(=O)CO)CC3)CC2 | | CAS DataBase Reference | 152-58-9(CAS DataBase Reference) |
| Hazard Codes | F,T | | Risk Statements | 11-23/24/25-39/23/24/25 | | Safety Statements | 24/25-22-45-36/37-16-7 | | RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | | WGK Germany | 3 | | RTECS | TU5011500 | | HS Code | 2937.23.5050 | | Storage Class | 11 - Combustible Solids | | Toxicity | mouse,LD50,intravenous,100mg/kg (100mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04684, |
| Provider | Language |
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ACROS
| English |
| | CORTEXOLONE Usage And Synthesis |
| Chemical Properties | Crystalline Solid | | Uses | 11-Deoxy Cortisol (Hydrocortisone EP Impurity F) is a glucocorticoid receptor binding. | | Definition | ChEBI: 11-deoxycortisol is a deoxycortisol that is cortisol in which the hydroxy group at position 11 has been replaced by a hydrogen. It has a role as a mouse metabolite and a human metabolite. It is a glucocorticoid, a primary alpha-hydroxy ketone, a tertiary alpha-hydroxy ketone and a deoxycortisol. | | in vivo | Cortodoxone (100 mg/kg; i.p.) increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone[1]. | Animal Model: | 220-320g, adult male Wistar rats[2] | | Dosage: | 100 mg/kg | | Administration: | IP | | Result: | Increased tryptophan oxygenase (TO) activity and induced the secretion of corticosterone. |
| | IC 50 | Human Endogenous Metabolite |
| | CORTEXOLONE Preparation Products And Raw materials |
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