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| | 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid Basic information |
| Product Name: | 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid | | Synonyms: | 2,2'-(1,2-Ethenediyl)bis(5-isothiocyanatobenzenesulfonic acid);4,4'-Bis(isothiocyanato)stilbene-2,2'-bissulfonic acid;4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid;4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid;4,4′-Diisotbiocyano-2,2′-stilbenedisulfnic Acid Disodium Salt;5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid;Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-isothiocyanato-;4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid | | CAS: | 53005-05-3 | | MF: | C16H10N2O6S4 | | MW: | 454.52 | | EINECS: | | | Product Categories: | Cross Linking Reagents;Fluorescent Labels & Indicators | | Mol File: | 53005-05-3.mol |  |
| | 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid Chemical Properties |
| Melting point | >400°C | | density | 1.54±0.1 g/cm3(Predicted) | | pka | -1.32±0.50(Predicted) |
| HazardClass | IRRITANT-HARMFUL |
| | 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid Usage And Synthesis |
| Chemical Properties | Yellow Crystalline Solid | | Uses | Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprot | | Uses | Ion channel inhibitor; especially of anion transport. | | Definition | ChEBI: 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid is an arenesulfonic acid. | | General Description | Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl– uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties. | | Biochem/physiol Actions | Primary TargetCl- uptake |
| | 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid Preparation Products And Raw materials |
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