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5-(4-Nitrophenyl)-2-furaldehyde

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5-(4-Nitrophenyl)-2-furaldehyde Basic information
Product Name:5-(4-Nitrophenyl)-2-furaldehyde
Synonyms:5-(4-NITROPHENYL)-2-FURANCARBOXALDEHYDE;5-(4-NITROPHENYL)-2-FURALDEHYDE;5-(4-NITRO-PHENYL)-FURAN-2-CARBALDEHYDE;5-(4-NITROPHENYL)-FURAN-2-CARBOXALDHYDE;5-(4-NITROPHENYL)FURFURAL;5-(p-Nitropheny) Furancarboxaldehyde;Nitrophenyl-2-furancarboxaldehyde;5-(4-Nitrophenyl)-2-Furancarbo
CAS:7147-77-5
MF:C11H7NO4
MW:217.18
EINECS:230-459-4
Product Categories:Aromatic Aldehydes & Derivatives (substituted);Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Building Blocks;C10-C12;C8 to C11;Carbonyl Compounds;Chemical Synthesis;Furans;Heterocyclic Building Blocks;Organic Building Blocks;Aldehydes;Furans, Benzofurans & Dihydrobenzofurans;Furans, Benzofurans & Dihydrobenzofurans
Mol File:7147-77-5.mol
5-(4-Nitrophenyl)-2-furaldehyde Structure
5-(4-Nitrophenyl)-2-furaldehyde Chemical Properties
Melting point 204-206 °C(lit.)
Boiling point 406.8±35.0 °C(Predicted)
density 1.348±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly, Heated), Ethyl Acetate (Slightly, Heated)
form Solid
color Yellow to Dark Yellow
Major Applicationpharmaceutical (small molecule)
InChIInChI=1S/C11H7NO4/c13-7-10-5-6-11(16-10)8-1-3-9(4-2-8)12(14)15/h1-7H
InChIKeyRTSOJVJDKNKNFU-UHFFFAOYSA-N
SMILESO1C(C2=CC=C([N+]([O-])=O)C=C2)=CC=C1C=O
CAS DataBase Reference7147-77-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 26-36
WGK Germany 3
HazardClass IRRITANT
HS Code 29329990
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
5-(4-Nitrophenyl)-2-furaldehyde Usage And Synthesis
Chemical Propertiesbrown crystalline powder
UsesA furfural nitrophenyl derivative as antibacterial and fungistatic agent.
Synthesis
Furfural

98-01-1

4-Nitroaniline

100-01-6

5-(4-Nitrophenyl)-2-furaldehyde

7147-77-5

The target compounds 5-(4-nitrophenyl)furan-2-carbaldehyde (1-9) were synthesized and structurally characterized using 2-furancarboxaldehyde and 4-nitroaniline as starting materials with reference to the methods described in literature [3,13].

References[1] Heterocyclic Communications, 2003, vol. 9, # 6, p. 625 - 628
[2] Tetrahedron, 2013, vol. 69, # 48, p. 10292 - 10298
[3] Chinese Journal of Chemistry, 2014, vol. 32, # 7, p. 637 - 644
[4] New Journal of Chemistry, 2015, vol. 39, # 9, p. 7206 - 7210
[5] Asian Journal of Chemistry, 2013, vol. 25, # 14, p. 7738 - 7742
5-(4-Nitrophenyl)-2-furaldehyde Preparation Products And Raw materials
Raw materialsFurfural-->4-Nitroaniline-->Hydrochloric acid-->Copper(II) chloride-->Water
Preparation ProductsN-{[5-(4-Nitrophenyl)furan-2-yl]methylidene}hydroxylamine
Tag:5-(4-Nitrophenyl)-2-furaldehyde(7147-77-5) Related Product Information
1-Phenyl-2-nitropropene Furfural 5-(4-Nitrophenyl)-2-furoic acid 5-(2-Methyl-4-nitrophenyl)furan-2-carbonyl chloride 5-(2-Methoxy-4-nitrophenyl)furan-2-carbonyl chloride 5-(2-Chloro-4-nitrophenyl)furan-2-carbonyl chloride 5-(4-Nitrophenyl)furan-2-carbonyl chloride 5-(3-Nitrophenyl)-2-furaldehyde 5-(2-Nitrophenyl)-2-furaldehyde 5-(2-Chloro-4-nitrophenyl)-2-furoic acid 5-(2-Chloro-4-nitro-phenyl)-furan-2-carbaldehyde 5-(2-Methoxy-4-nitro-phenyl)-furan-2-carbaldehyde 5-(2-Methoxy-5-nitro-phenyl)-furan-2-carbaldehyde 5-(2-Bromo-4-nitro-phenyl)-furan-2-carbaldehyde 5-(2-Methyl-4-nitrophenyl)-furan-2-carboxylic acid [3-(5,7-dimethylbenzooxazol-2-yl)phenyl]amide 5-(2-Methyl-4-nitro-phenyl)-furan-2-carboxylic acid 5-(2-Methyl-4-nitrophenyl)-2-furaldehyde 5-(2-Methyl-4-nitro-phenyl)-furan-2-carboxylic acid benzylamide