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| | 15(R)-15-Methyl prostaglandin A2 Basic information |
| Product Name: | 15(R)-15-Methyl prostaglandin A2 | | Synonyms: | 9-Oxo-15R-hydroxy-15-hethyl-prosta-5Z,10,13E-trien-1-oic acid;UEBXYYKXJUBAJX-ULDSDQABSA-N;9-OXO-15R-HYDROXY-15-METHYL-PROSTA-5Z,10,13E-TRIEN-1-OIC ACID;Reaxys ID: 3005095;Prosta-5,10,13-trien-1-oic acid, 15-hydroxy-15-methyl-9-oxo-, (5Z,13E,15R)-;15(R)-15-Methyl prostaglandin A2 | | CAS: | 96440-68-5 | | MF: | C21H32O4 | | MW: | 348.48 | | EINECS: | | | Product Categories: | | | Mol File: | 96440-68-5.mol |  |
| | 15(R)-15-Methyl prostaglandin A2 Chemical Properties |
| Boiling point | 520.9±50.0 °C(Predicted) | | density | 1.091±0.06 g/cm3(Predicted) | | solubility | DMF: >75 mg/ml (from PGA1); DMSO: >50 mg/ml (from PGA1); Ethanol: >100 mg/ml (from PGA1); PBS pH 7.2: >2.4 mg/ml (from PGA1) | | pka | 4.75±0.10(Predicted) |
| | 15(R)-15-Methyl prostaglandin A2 Usage And Synthesis |
| Description | Arbaprostil (15(R)-15-methyl prostaglandin E2) is a synthetic prostaglandin E2 (PGE2) analog developed for its cytoprotective activity.1 15(R)-15-methyl Prostaglandin A2 (15(R)-15-methyl PGA2) is one of several impurities which are possible in the production of commercial lots of bulk arbaprostil.2 The pharmacology and EP receptor binding affinity for 15(R)-15-methyl PGA2 has not been published. | | Uses | 15(R)-15-Methyl prostaglandin A2 is a biochemical reagent. | | Definition | ChEBI: 15(R)-15-methyl Prostaglandin A2 is a prostanoid. | | References | 1. Collins, P.W. Misoprostol: Discovery, development, and clinical applications Med. Res. Rev. 10(2),149-172(1990). 2. Kissinger, L.D., and Robins, R.H. Silver-modified mobile phase for normal-phase liquid chromatographic determination of prostaglandins and their 5,6-trans isomers in prostaglandin bulk drugs and triacetin solutions J. Chromatogr. 321(2),353-362(1985). |
| | 15(R)-15-Methyl prostaglandin A2 Preparation Products And Raw materials |
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