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| | 5-Methyl-7-methoxyisoflavone Basic information |
| Product Name: | 5-Methyl-7-methoxyisoflavone | | Synonyms: | METHYL-7-METHOXY-ISOFLAVONE, 5-;5-METHYL-7-METHOXYISOFLAVONE;7-METHOXY-5-METHYLISOFLAVONE;5-METHYL-7-METHOXYISOFLAVONE 99+%;5-Methyl-7-methoxyisoflavone 98.0%min;5-Methyl-7-methoxyisoflavone,98%;5-Methyl-7-methoxyis;7-methoxy-5-methyl-3-phenyl-1-benzopyran-4-one | | CAS: | 82517-12-2 | | MF: | C17H14O3 | | MW: | 266.29 | | EINECS: | 617-342-7 | | Product Categories: | Heterocycles;Iso-Flavones;82517-12-2 | | Mol File: | 82517-12-2.mol |  |
| | 5-Methyl-7-methoxyisoflavone Chemical Properties |
| Melting point | 116-120 °C | | Boiling point | 349.5°C (rough estimate) | | density | 1.2327 (rough estimate) | | refractive index | 1.4500 (estimate) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly, Sonicated) | | form | Solid | | color | White to Off-White | | LogP | 4.242 (est) | | CAS DataBase Reference | 82517-12-2(CAS DataBase Reference) |
| Safety Statements | 24/25 | | HS Code | 29145000 |
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ACROS
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| | 5-Methyl-7-methoxyisoflavone Usage And Synthesis |
| Chemical Properties | white crystalline powder | | Uses | 5-Methyl-7-methoxyisoflavone is an orally active anti-oxidant with remyelinating activity. 5-Methyl-7-methoxyisoflavone inhibits the enzyme aromatase, interfering with the normal metabolic pathways of testosterone. 5-Methyl-7-methoxyisoflavone is a non-steroidal anabolic isoflavone, used as a anabolic agent. 5-Methyl-7-methoxyisoflavone shows better potency increasing muscle mass and endurance than Ipriflavone (HY-N0094). 5-Methyl-7-methoxyisoflavone can be used for fat loss besides the maintenance of low cholesterol level and strengthen bones. 5-Methyl-7-methoxyisoflavone is the inhibitor for NF-κB[1][2][3][4]. | | References | [1] Ningbo Gong, et al. Concomitant polymorphs of methoxyflavone (5-methyl-7-methoxyflavone). RSC Adv., 2016, 6, 38709-38715.
[2] Agresti C, et al. Oxidative status in multiple sclerosis and off-targets of antioxidants: the case of edaravone[J]. Current Medicinal Chemistry, 2020, 27(13): 2095-2105. DOI:10.2174/0929867326666190124122752
[3] Iannone M, et al. An investigation on the metabolic pathways of synthetic isoflavones by gas chromatography coupled to high accuracy mass spectrometry. Rapid Commun Mass Spectrom. 2019 Oct 15;33(19):1485-1493. DOI:10.1002/rcm.8490
[4] Lecompte Y, et al. UPLC-ESI-Q-TOF-MS(E) identification of urinary metabolites of the emerging sport nutrition supplement methoxyisoflavone in human subjects. J Pharm Biomed Anal. 2014 Aug 5;96:127-34. DOI:10.1016/j.jpba.2014.03.031
[5] Lee S, et al., Isoflavone derivatives inhibit NF-κB-dependent transcriptional activity. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6277-81. DOI:10.1016/j.bmcl.2010.08.089
[6] Hyun J, et al., Isoflavones inhibit the clonogenicity of human colon cancer cells. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2664-9. DOI:10.1016/j.bmcl.2012.03.027 |
| | 5-Methyl-7-methoxyisoflavone Preparation Products And Raw materials |
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