EST64454 Maleic acid salt

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EST64454 Maleic acid salt Basic information
Product Name:EST64454 Maleic acid salt
Synonyms:EST64454 Maleic acid salt;EST-64454 Maleic acid salt,EST64454 Maleic acid salt;EST64454 Maleic acid salt, 10 mM in DMSO
CAS:2088272-67-5
MF:C22H26F2N4O6
MW:480.47
EINECS:
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Mol File:2088272-67-5.mol
EST64454 Maleic acid salt Structure
EST64454 Maleic acid salt Chemical Properties
Safety Information
MSDS Information
EST64454 Maleic acid salt Usage And Synthesis
UsesEST64454 maleate is a highly soluble σ1 receptor antagonist, demonstrating potent antinociceptive properties for pain treatment. EST64454 maleate exhibits excellent metabolic stability across various species and possesses an adequate pharmacokinetic profile in rodents. EST64454 maleate has been identified as a promising clinical candidate due to its favorable aqueous solubility and high permeability in Caco-2 cells.
References[1] EST64454: a Highly Soluble σ1 Receptor Antagonist Clinical Candidate for Pain Management DOI:10.1021/acs.jmedchem.0c01575
EST64454 Maleic acid salt Preparation Products And Raw materials
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