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Penbutolol

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Penbutolol Suppliers list
Company Name: BOC Sciences  
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Company Name: TargetMol Chemicals Inc.  
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Company Name: BOC Sciences  
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Company Name: TCI (Shanghai) Chemical Trading Co., Ltd.  
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Company Name: TargetMol Chemicals Inc.  
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Penbutolol manufacturers

  • Penbutolol
  • Penbutolol pictures
  • $1980.00
  • 2026-05-11
  • CAS:38363-40-5
  • Purity:
  • Supply Ability: 10g
  • Penbutolol
  • Penbutolol pictures
  • $1980.00
  • 2025-07-23
  • CAS:38363-40-5
  • Purity:
  • Supply Ability: 10g
Penbutolol Basic information
Product Name:Penbutolol
Synonyms:(-)-(S)-Penbutolol;2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-, (2S)- (9CI);2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-, (S)-;Betapressin;HOE 893;HOE 893D;Levopenbutolol;l-Penbutolol
CAS:38363-40-5
MF:C18H29NO2
MW:291.43
EINECS:
Product Categories:
Mol File:38363-40-5.mol
Penbutolol Structure
Penbutolol Chemical Properties
Melting point 68-72°
alpha 20D -11.5° (c = 1 in methanol)
Boiling point 433.43°C (rough estimate)
density 1.0344 (rough estimate)
refractive index 1.5000 (estimate)
pka9.3 (1.5 mmol/l in 25% ethanol)
color Crystals
Water Solubility 7g/L(room temperature)
Safety Information
ToxicityLD50 oral in rabbit: 300mg/kg
MSDS Information
Penbutolol Usage And Synthesis
OriginatorBetapressin, Hoechst , W. Germany ,1980
UsesAnti-adrenergic (β-receptor).
DefinitionChEBI: Penbutolol is a member of ethanolamines.
Manufacturing Process21.8 g (0.1 mol) of 1,2-epoxy-3-(2'-cyclopentylphenoxy)propane, boiling at 113°C to 115°C/0.2 mm Hg (prepared from 2-cyclopentylphenol and epichlorhydrin in the presence of alkali) were dissolved in 250 ml of ethanol; to this solution, there were added dropwise, while stirring.8.9 g (0.15 mol) of t-butylamine. The reaction mixture was stirred for 2 hours at 60°C and then the solvent and the excess t-butylamine were removed by distillation. The residue which had been purified via the aqueous hydrochloride, crystallized, after removal of the ether by evaporation, upon rubbing or inoculation and yielded, after recrystallization from n-heptane, the 1-t-butylamino-2-hydroxy3-(2'-cyclopentylphenoxy)propane which was found to melt at 69°C to 70°C.
Brand nameLevatol(Schwarz Pharma).
Therapeutic FunctionBeta-adrenergic blocker
Safety ProfilePoison by ingestion and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Penbutolol Preparation Products And Raw materials
Raw materialstert-Butylamine-->Epichlorohydrin-->2-Cyclopentylphenol
Tag:Penbutolol(38363-40-5) Related Product Information
Felodipine Bisoprolol Penbutolol impurity A(2S)-1-[2-(cyclopent-1-enyl)phenoxy]-3-[(1,1-dimethylethyl)amino]propan-2-ol epp(CRM standard) (+)-(R)-Penbutolol,(R)-Penbutolol,d-Penbutolol PENBUTOLOL IMPURITY A PENBUTOLOL SULFATE USP(CRM STANDARD) PENBUTOLOL SULPHATE EPP(CRM STANDARD) PENBUTOLOL SULPHATE PENBUTOLOL SULFATE (200 MG)