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| | (2,3-epoxyphytyl)menaquinone Basic information |
| Product Name: | (2,3-epoxyphytyl)menaquinone | | Synonyms: | (2,3-epoxyphytyl)menaquinone;1a,7a-Dihydro-1a-methyl-7a-(3,7,11,15-tetramethyl-2-hexadecenyl)naphth[2,3-b]oxirene-2,7-dione;Vitamin K 2,3-epoxide;1,4-Naphthoquinone,2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-2,3-epoxyphylloquinone;2,3-Epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone;1a,7a-Dihydro-1a-methyl-7a-(3,7,11,15-tetramethyl-2-hexadecen-1-yl)-naphth[2,3-b]oxirene-2,7-dione;Phylloquinone Oxid;Vitamin K Epoxide | | CAS: | 25486-55-9 | | MF: | C31H46O3 | | MW: | 466.7 | | EINECS: | 247-022-9 | | Product Categories: | Vitamins and derivatives;Inhibitors;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Various Metabolites and Impurities | | Mol File: | 25486-55-9.mol |  |
| | (2,3-epoxyphytyl)menaquinone Chemical Properties |
| storage temp. | -20°C | | solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) | | Boiling point | 561.1±50.0 °C(Predicted) | | density | 1.019±0.06 g/cm3(Predicted) | | form | Oil | | color | Colourless to Pale Yellow | | Cosmetics Ingredients Functions | SKIN PROTECTING
ASTRINGENT | | InChI | InChI=1S/C31H46O3/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-31-29(33)27-19-8-7-18-26(27)28(32)30(31,6)34-31/h7-8,18-20,22-24H,9-17,21H2,1-6H3 | | InChIKey | KUTXFBIHPWIDJQ-UHFFFAOYSA-N | | SMILES | O1C2(CC=C(C)CCCC(C)CCCC(C)CCCC(C)C)C(=O)C3=C(C(=O)C12C)C=CC=C3 |
| WGK Germany | WGK 3 | | Storage Class | 10 - Combustible liquids |
| | (2,3-epoxyphytyl)menaquinone Usage And Synthesis |
| Description | Vitamin K is a dietary nutrient essential for the normal biosynthesis of factors that are required for blood clotting. It has also been shown to inhibit cell growth. Vitamin K1 2,3-epoxide is the inactive metabolite of vitamin K1. During clotting, vitamin K1 is converted to this epoxide form and then rapidly reduced back to the vitamin by a microsomal epoxide reductase. This is referred to as the vitamin K epoxide cycle. Certain anticoagulants target clotting factor synthesis by inhibiting the recycling of vitamin K1 from the inactive epoxide. | | Chemical Properties | Clear Colourless to Pale Yellow Oil | | Uses | A metabolite of Vitamin K1 (V676080). | | Biochem/physiol Actions | Vitamin K1 2,3-epoxide is a vitamin K derivative. It is a fat soluble vitamin produced by plants. Vitamin K is essential for blood coagulation. Vitamin K is rarely deficient in a human diet since it is continually recycled in our cells. Vitamin K 2,3-epoxide acts as a substrate for vitamin K 2,3-epoxide reductase (VKOR) complex. Elevated levels of serum vitamin K epoxide in patients is associated with familial multiple coagulation factor deficiency. | | References | [1] IA CHOONARA. The relationship between inhibition of vitamin K1 2,3-epoxide reductase and reduction of clotting factor activity with warfarin.[J]. British journal of clinical pharmacology, 1988, 25 1: 1-7. DOI: 10.1111/j.1365-2125.1988.tb03274.x |
| | (2,3-epoxyphytyl)menaquinone Preparation Products And Raw materials |
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