N'-benzylpivalohydrazide manufacturers
|
| | N'-benzylpivalohydrazide Basic information |
| Product Name: | N'-benzylpivalohydrazide | | Synonyms: | N'-benzylpivalohydrazide;pivalylbenzhydrazine;2,2-Dimethyl-N'-(phenylmethyl)propanoic acid hydrazide;Angorvit;Ro 4-1634;2,2-Dimethylpropanoic acid 2-(phenylmethyl)hydrazide;Betamezid;Betamezide | | CAS: | 306-19-4 | | MF: | C12H18N2O | | MW: | 206.28 | | EINECS: | 206-180-9 | | Product Categories: | | | Mol File: | 306-19-4.mol |  |
| | N'-benzylpivalohydrazide Chemical Properties |
| Melting point | 68-69° | | Boiling point | 296.1±23.0 °C(Predicted) | | density | 1.015±0.06 g/cm3(Predicted) | | pka | 13.41±0.50(Predicted) |
| RIDADR | 3249 | | HazardClass | 6.1(b) | | PackingGroup | III | | Toxicity | mouse,LD50,intravenous,> 280mg/kg (280mg/kg),Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963. |
| | N'-benzylpivalohydrazide Usage And Synthesis |
| Uses | Pivalylbenzhydrazine (Pivhydrazine) is a potent monoamine oxidase (MAO) inhibitor. Pivalylbenzhydrazine decreases cartilage growth in normal rats. Pivalylbenzhydrazine can be used in research of depression[1]. | | Definition | ChEBI: Pivhydrazine is a member of benzenes. | | in vivo | Pivalylbenzhydrazine (Pivhydrazine; 5 mg/kg; i.p.; daily, for 5 d; immature female rats) inhibits the growth of the epiphysial cartilage[1]. | Animal Model: | Immature female rats (40 g, 3-4 weeks age)[1] | | Dosage: | 5 mg/kg | | Administration: | Intraperitoneal injection; daily, for 5 days | | Result: | Inhibited the growth of the epiphysial cartilage |
| | References | [1] Zor U, et, al. The effect of monoamine oxidase inhibitors on growth and the rat tibia test. J Endocrinol. 1965 Apr;32:35-43. DOI:10.1677/joe.0.0320035 |
| | N'-benzylpivalohydrazide Preparation Products And Raw materials |
|