ciclonicate manufacturers
- Ciclonicate
-
- $2500.00
-
2026-05-11
- CAS:53449-58-4
- Purity:
- Supply Ability: 10g
|
| | ciclonicate Basic information |
| Product Name: | ciclonicate | | Synonyms: | ciclonicate;Cortofludan;Cyclonicate;rel-3-Pyridinecarboxylic acid (1S*)-3,3,5β*-trimethylcyclohexane-1α*-yl ester;3-Pyridinecarboxylic acid, (1R,5S)-3,3,5-trimethylcyclohexyl ester, rel-;Elastan;P-350;Rolil | | CAS: | 53449-58-4 | | MF: | C15H21NO2 | | MW: | 247.33 | | EINECS: | 2585614 | | Product Categories: | | | Mol File: | 53449-58-4.mol |  |
| | ciclonicate Chemical Properties |
| Melting point | <25 °C | | Boiling point | bp0.6 127-128° | | density | 1.06±0.1 g/cm3(Predicted) | | pka | 3.14±0.10(Predicted) |
| | ciclonicate Usage And Synthesis |
| Originator | Bled, Poli, Italy ,1978 | | Definition | ChEBI: Ciclonicate is an aromatic carboxylic acid and a member of pyridines. | | Manufacturing Process | To a solution of 142 g (1 mol) of trans-3,3,5-trimethylcyclohexanol in 400 cc
of anhydrous benzene heated to 70 C is added gradually 178 g (1 mol) of
niacin chloride hydrochloride. Heating is carried out under reflux conditions for
3 hours, the solution is cooled, the ester hydrochloride is filtered off and then
recrystallized in an ethanol-ethyl ether mixture to obtain 227 g (80% yield) of
product melting at 155°C to 157°C.
By treating the hydrochloride with an aqueous solution of NaOH at 0°C, the
free base is obtained in the form of a viscous white liquid which boils at 115°C
under 0.05 mm. | | Therapeutic Function | Vasodilator |
| | ciclonicate Preparation Products And Raw materials |
|