N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri din-4-yl)benzoyl]piperidine-3-carboxamide

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N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri din-4-yl)benzoyl]piperidine-3-carboxamide Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
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Products Intro: Product Name:CCG-257081；CCG257081;CCG 257081
CAS:1922098-90-5
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
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Products Intro: Product Name:N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri din-4-yl)benzoyl]piperidine-3-carboxamide
CAS:1922098-90-5
Purity:95% HPLC Package:1g;5g;10g;
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
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Email: customer_service@efebio.com
Products Intro: Product Name:CCG-257081
CAS:1922098-90-5
Purity:99.00% Package:1mg;5mg;10mg
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:CCG-257081
CAS:1922098-90-5
Purity:99.87% Package:1removed
Company Name: Sangon Biotech (Shanghai) Co.,Ltd.  
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Products Intro: Product Name:CCG-257081
CAS:1922098-90-5
N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri din-4-yl)benzoyl]piperidine-3-carboxamide Basic information
Product Name:N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri din-4-yl)benzoyl]piperidine-3-carboxamide
Synonyms:N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri din-4-yl)benzoyl]piperidine-3-carboxamide;CCG 257081;CCG257081;CCG-257081;3-Piperidinecarboxamide, N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(4-pyridinyl)benzoyl]-;MRTF/SRF-IN-1
CAS:1922098-90-5
MF:C24H19ClF3N3O2
MW:473.87
EINECS:
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Mol File:1922098-90-5.mol
N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri din-4-yl)benzoyl]piperidine-3-carboxamide Structure
N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri din-4-yl)benzoyl]piperidine-3-carboxamide Chemical Properties
Boiling point 689.1±55.0 °C(Predicted)
density 1.42±0.1 g/cm3(Predicted)
form Solid
pka13.69±0.70(Predicted)
color White to off-white
Safety Information
MSDS Information
N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri din-4-yl)benzoyl]piperidine-3-carboxamide Usage And Synthesis
DescriptionCCG-257081 is an inihibitor of Rho/MRTF/SRF pathway. CCG-257081 has shown efficacy in preventing bleomycin-induced fibrosis in several mouse models.
UsesMRTF/SRF-IN-1 (example 41) is an inhibitor of both myocardin-related transcription factor and serum response factor (MRTF/SRF). MRTF/SRF-IN-1 can be used for research for preventing cancer and fibrosis[1].
References[1] Larsen Scott D, et al. Preparation of substituted piperidine-3-carboxamides as inhibitors of myocardin-related transcription factor and serum response factor (MTRF/SRF)-mediated gene transcription. World Intellectual Property Organization, WO2016073847 A2. 2016-05-12.
N-(4-chlorophenyl)-5,5-difluoro-1-[3-fluoro-5-(pyri din-4-yl)benzoyl]piperidine-3-carboxamide Preparation Products And Raw materials
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