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| | Enadoline Basic information |
| Product Name: | Enadoline | | Synonyms: | Enadoline;N-[(5R,7S,8S)-7α-(1-Pyrrolidinyl)-1-oxaspiro[4.5]decane-8β-yl]-N-methylbenzofuran-4-acetamide;N-[[5R,7S,8S,(-)]-7α-(1-Pyrrolidinyl)-1-oxaspiro[4.5]decane-8β-yl]-N-methylbenzofuran-4-acetamide;N-[[5R,7S,8S,(+)]-7α-(1-Pyrrolidinyl)-1-oxaspiro[4.5]decan-8β-yl]-N-methylbenzofuran-4-acetamide;4-Benzofuranacetamide, N-methyl-N-((5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)-;4-Benzofuranacetamide, N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)-, (5R-(5alpha,7alpha,8beta))-;Enadoline [inn];Unii-kjl283326c | | CAS: | 124378-77-4 | | MF: | C24H32N2O3 | | MW: | 396.52 | | EINECS: | | | Product Categories: | | | Mol File: | 124378-77-4.mol |  |
| | Enadoline Chemical Properties |
| Boiling point | 563.2±50.0 °C(Predicted) | | density | 1.20±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 9.15±0.20(Predicted) |
| | Enadoline Usage And Synthesis |
| Uses | Enadoline is a selective kappa opioid agonist. It exhibits antihyperalgesic and antiallodynic properties. | | Brand name | Analgesic. | | in vivo | Enadoline (i.v.; dose of e 15 min before surgery; male Sprague-Dawley rats) dose-dependently (1-100 μg/kg) blocks the development of thermal hyperalgesia as well as static and dynamic allodynia for over 24 h with respective MEDs (minimum effective doses) of < or = 1, 10 and 10 μg/kg[2]. |
| | Enadoline Preparation Products And Raw materials |
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