| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
Metoprine manufacturers
- Metoprine
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- $55.00
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2026-06-02
- CAS:7761-45-7
- Purity: 99.09%
- Supply Ability: 10g
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| | Metoprine Basic information |
| | Metoprine Chemical Properties |
| Melting point | 275-276℃ | | Boiling point | 418.42°C (rough estimate) | | density | 1.447 | | refractive index | 1.6300 (estimate) | | storage temp. | Hygroscopic, Refrigerator, under inert atmosphere | | solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated) | | form | Solid | | pka | 6.80±0.10(Predicted) | | color | Off-White to Light Yellow | | Stability: | Hygroscopic |
| | Metoprine Usage And Synthesis |
| Uses | A 2,4-Diaminopyrimidine derivative as antimalarial agent. | | in vivo | Metoprine (BW 197U; 2-10 mg/kg; IP) ameliorates the memory deficits induced by nucleus basalis magnocellularis (NBM) lesions in a dose-dependent manner[2].
Intraperitoneal administration of Metoprine produces various behavioral effects, including decreases in food intake and increases in water consumption[1].
| Animal Model: | Male Sprague-dawley rats (200-280g)[2] | | Dosage: | 2, 5, 10 mg/kg | | Administration: | IP | | Result: | Ameliorated the memory deficits induced by nucleus basalis magnocellularis (NBM) lesions in a dose-dependent manner and significanty prolonged transfer latency at a high dose of 10 mg/kg.
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| | Metoprine Preparation Products And Raw materials |
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