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7-Hydroxy-5-methyl-1,3,4-triazaindolizine

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CAS:2503-56-2
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CAS:2503-56-2
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7-Hydroxy-5-methyl-1,3,4-triazaindolizine manufacturers

7-Hydroxy-5-methyl-1,3,4-triazaindolizine Basic information
Product Name:7-Hydroxy-5-methyl-1,3,4-triazaindolizine
Synonyms:2,4]Triazolo[1,5-a]pyrimidin-7-ol,5-methyl-[1;5-a)pyrimidin-7-ol,5-methyl-s-triazolo(;5-Methyl-7-hydroxy-1,3,4-triazindolizine;5-Methyl-s-trazolo[1,5-]pyrimidin-7-ol;Methyl hydroxytriazaindolizine;5-Methyl-s-triazolo[1,5-a]pyrimidin-7-ol,98%;5-Methyl (1,2,4)trizolo(1,5-α)pyrimidin-7-ol;5-Methyl-[1,2,4]triazolo[1,5-a]pyridin-7-ol
CAS:2503-56-2
MF:C6H6N4O
MW:150.14
EINECS:219-706-7
Product Categories:Industrial/Fine Chemicals;Benzotriazoles;Building Blocks;C-C Bond Formation;Chemical Synthesis;Heterocyclic Building Blocks;Others;Synthetic Reagents
Mol File:2503-56-2.mol
7-Hydroxy-5-methyl-1,3,4-triazaindolizine Structure
7-Hydroxy-5-methyl-1,3,4-triazaindolizine Chemical Properties
Melting point 280-283 °C(lit.)
Boiling point 271.66°C (rough estimate)
density 1.3471 (rough estimate)
vapor pressure 0-0Pa at 20-25℃
refractive index 1.6700 (estimate)
storage temp. 2-8°C
pka1.14±0.53(Predicted)
form solid
color White to Almost white
Water Solubility INSOLUBLE IN COLD WATER
BRN 609440
InChI1S/C6H6N4O/c1-4-2-5(11)10-6(9-4)7-3-8-10/h2-3,11H,1H3
InChIKeyZUIVNYGZFPOXFW-UHFFFAOYSA-N
SMILESCc1cc(O)n2ncnc2n1
LogP-1.4 at 19℃ and pH7.1
CAS DataBase Reference2503-56-2(CAS DataBase Reference)
NIST Chemistry ReferencePyrimidin-7-ol, 5-methyl-s-triazolo-[1,5-a]-(2503-56-2)
EPA Substance Registry System[1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 5-methyl- (2503-56-2)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 1
RTECS XZ6133300
9
Hazard Note Harmful
TSCA TSCA listed
HS Code 2933998090
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Irrit. 2
Skin Irrit. 2
STOT SE 3
Toxicitymouse,LD50,intravenous,> 450mg/kg (450mg/kg),Oyo Yakuri. Pharmacometrics. Vol. 13, Pg. 597, 1977.
MSDS Information
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7-Hydroxy-5-methyl-1,3,4-triazaindolizine English
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7-Hydroxy-5-methyl-1,3,4-triazaindolizine Usage And Synthesis
Chemical Properties7-Hydroxy-5-methyl-1,3,4-triazaindolizine is white fine crystalline powder
UsesReactant for the synthesis of: • ;Ruthenium(II)-Hmtpo complexes1• ;Dihydroorotate dehydrogenase inhibitors with antimalarial activity2Reactant for the Vilsmeier reaction of conjugated carbocycles and heterocycles3Investigations of the pharmacological activity caused by binding to HIV TAR RNA4Additive to study the space charge layer in silver bromide microcrystals5
UsesReactant for the synthesis of:
  • Ruthenium(II)-Hmtpo complexes
  • Dihydroorotate dehydrogenase inhibitors with antimalarial activity

Reactant for the Vilsmeier reaction of conjugated carbocycles and heterocycles

Investigations of the pharmacological activity caused by binding to HIV TAR RNA

Additive to study the space charge layer in silver bromide microcrystals
reaction suitabilityreaction type: C-C Bond Formation
7-Hydroxy-5-methyl-1,3,4-triazaindolizine Preparation Products And Raw materials
Raw materials3-Amino-1,2,4-Triazole-->Ethyl acetoacetate
Tag:7-Hydroxy-5-methyl-1,3,4-triazaindolizine(2503-56-2) Related Product Information
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