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Tenidap

Tenidap Suppliers list
Company Name: J & K SCIENTIFIC LTD.  
Tel: 18210857532 18210857532
Email: jkinfo@jkchemical.com
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 18930552037
Email: 3bsc@sina.com
Company Name: LGM Pharma  
Tel: 1-(800)-881-8210
Email: inquiries@lgmpharma.com
Company Name: Chemsky(shanghai)International Co.,Ltd.  
Tel: 021-50135380
Email: shchemsky@sina.com
Company Name: Guangzhou Isun Pharmaceutical Co., Ltd  
Tel: 020-39119399 18927568969
Email: isunpharm@qq.com

Tenidap manufacturers

  • TENIDAP
  • TENIDAP pictures
  • 2026-09-14
  • CAS:120210-48-2
  • Min. Order: 1kg
  • Purity: 99% up by hplc
  • Supply Ability: 20tons
  • TENIDAP USP/EP/BP
  • TENIDAP USP/EP/BP pictures
  • $1.10
  • 2026-08-20
  • CAS:120210-48-2
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons Min
  • Tenidap
  • Tenidap pictures
  • $30.00
  • 2026-07-14
  • CAS:120210-48-2
  • Purity: 99.43%
  • Supply Ability: 10g
Tenidap Basic information
Product Name:Tenidap
Synonyms:TENIDAP;AKOS 91367;5-Chloro-2,3-dihydro-2-oxo-3-(2-thenoyl)-1H-indole-1-carboxamide;CP66248,CP-66248-2;(3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H-indole-1-carboxaMide;(Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H- indole-1-carboxaMide;1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (3Z)-;TENIDAP USP/EP/BP
CAS:120210-48-2
MF:C14H9ClN2O3S
MW:320.75
EINECS:
Product Categories:
Mol File:120210-48-2.mol
Tenidap Structure
Tenidap Chemical Properties
Melting point 230° (dec)
Boiling point 538.1±60.0 °C(Predicted)
density 1.648±0.06 g/cm3(Predicted)
storage temp. Store at +4°C
solubility DMSO: soluble1mg/mL, clear (warmed)
form powder
pka4.50±1.00(Predicted)
color faint yellow to dark yellow
InChI1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,19H,(H2,16,20)
InChIKeyIZSFDUMVCVVWKW-UHFFFAOYSA-N
SMILES[s]1c(ccc1)C(=O)c2c3c([n](c2O)C(=O)N)ccc(c3)Cl
Safety Information
Hazard Codes Xn
Risk Statements 22
WGK Germany 3
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
MSDS Information
Tenidap Usage And Synthesis
Chemical PropertiesFluffy and yellow crystals from acetic acid, melting point 230°C (decomposition). Tenidap Sodium (Tenidap Sodium): C14H8C1N2NaO3S.[119784-94-0]. Crystallized from methanol-isopropanol, melting point 237-238°C.
UsesAnti-inflammatory (osteoarthritis and rheumatoid arthritis).
UsesTenidap is one of the nonsteroidal antiinflammatory drugs (NSAIDs). Tenidap is an NSAID that preferentially inhibits COX-1. Tenidap inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes.
DefinitionChEBI: Tenidap is a member of indoles, a member of ureas, a member of thiophenes and an organochlorine compound. It has a role as a non-steroidal anti-inflammatory drug and an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor.
Biological ActivityNSAID that preferentially inhibits COX-1 (IC 50 values are < 0.03, 1.2 and > 30 μ M for COX-1, COX-2 and 5-lipoxygenase respectively). Inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes. Opener of inward rectifying hK IR 2.3 channel (EC 50 = 402 nM).
storageStore at +4°C
Mode of actionTenidap is an anti-inflammatory agent developed by Pfizer with a unique structure that is different and distinguishable from NSAIDs. The mechanism of action of tenidap is that it has dual inhibitory effects on lipoxygenase and dioxygenase, and has antagonism on interleukin-1 (IL-1).
Tag:Tenidap(120210-48-2) Related Product Information
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