Tenidap manufacturers
- Tenidap
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- $30.00 / 1mg
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2026-04-24
- CAS:120210-48-2
- Min. Order:
- Purity: 99.43%
- Supply Ability: 10g
- TENIDAP
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- $0.00 / 1kg
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2026-04-23
- CAS:120210-48-2
- Min. Order: 1kg
- Purity: 99% up by hplc
- Supply Ability: 20tons
- TENIDAP USP/EP/BP
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- $1.10 / 1g
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2025-11-18
- CAS:120210-48-2
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
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| | Tenidap Basic information |
| Product Name: | Tenidap | | Synonyms: | TENIDAP;AKOS 91367;5-Chloro-2，3-dihydro-2-oxo-3-(2-thenoyl)-1H-indole-1-carboxamide;CP66248,CP-66248-2;(3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H-indole-1-carboxaMide;(Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H-
indole-1-carboxaMide;1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (3Z)-;TENIDAP USP/EP/BP | | CAS: | 120210-48-2 | | MF: | C14H9ClN2O3S | | MW: | 320.75 | | EINECS: | | | Product Categories: | | | Mol File: | 120210-48-2.mol |  |
| | Tenidap Chemical Properties |
| Melting point | 230° (dec) | | Boiling point | 538.1±60.0 °C(Predicted) | | density | 1.648±0.06 g/cm3(Predicted) | | storage temp. | Store at +4°C | | solubility | DMSO: soluble1mg/mL, clear (warmed) | | form | powder | | pka | 4.50±1.00(Predicted) | | color | faint yellow to dark yellow | | InChI | 1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,19H,(H2,16,20) | | InChIKey | IZSFDUMVCVVWKW-UHFFFAOYSA-N | | SMILES | [s]1c(ccc1)C(=O)c2c3c([n](c2O)C(=O)N)ccc(c3)Cl |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | Tenidap Usage And Synthesis |
| Chemical Properties | Fluffy and yellow crystals from acetic acid, melting point 230°C (decomposition). Tenidap Sodium (Tenidap Sodium): C14H8C1N2NaO3S.[119784-94-0]. Crystallized from methanol-isopropanol, melting point 237-238°C. | | Uses | Anti-inflammatory (osteoarthritis
and rheumatoid arthritis). | | Uses | Tenidap is one of the nonsteroidal antiinflammatory drugs (NSAIDs). Tenidap is an NSAID that preferentially inhibits COX-1. Tenidap inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes. | | Definition | ChEBI: Tenidap is a member of indoles, a member of ureas, a member of thiophenes and an organochlorine compound. It has a role as a non-steroidal anti-inflammatory drug and an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. | | Biological Activity | NSAID that preferentially inhibits COX-1 (IC 50 values are < 0.03, 1.2 and > 30 μ M for COX-1, COX-2 and 5-lipoxygenase respectively). Inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes. Opener of inward rectifying hK IR 2.3 channel (EC 50 = 402 nM). | | storage | Store at +4°C | | Mode of action | Tenidap is an anti-inflammatory agent developed by Pfizer with a unique structure that is different and distinguishable from NSAIDs. The mechanism of action of tenidap is that it has dual inhibitory effects on lipoxygenase and dioxygenase, and has antagonism on interleukin-1 (IL-1). |
| | Tenidap Preparation Products And Raw materials |
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