1H-Imidazole-2-carboxylic acid, 1-[3-(dimethylamino)propyl]-5,5-di-(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester

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1H-Imidazole-2-carboxylic acid, 1-[3-(dimethylamino)propyl]-5,5-di-(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester Suppliers list
Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
Tel: +86-156-80926068 +86-15680926068
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Company Name: Shanghai Changyu Medical Technology Co. Ltd.  
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Company Name: DC Chemicals  
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Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
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Company Name: Bide Pharmatech Ltd.  
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1H-Imidazole-2-carboxylic acid, 1-[3-(dimethylamino)propyl]-5,5-di-(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester Basic information
Product Name:1H-Imidazole-2-carboxylic acid, 1-[3-(dimethylamino)propyl]-5,5-di-(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester
Synonyms:1H-Imidazole-2-carboxylic acid, 1-[3-(dimethylamino)propyl]-5,5-di-(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester;A12-lso5-2DC12;A12-Iso5-2DC18;Ethyl 1-(3-(dimethylamino)propyl)-5,5-di((Z)-heptadec-8-en-1-yl)-2,5-dihydro-1H-imidazole-2-carboxylate
CAS:2412492-06-7
MF:C45H85N3O2
MW:700.18
EINECS:
Product Categories:
Mol File:2412492-06-7.mol
1H-Imidazole-2-carboxylic acid, 1-[3-(dimethylamino)propyl]-5,5-di-(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester Structure
1H-Imidazole-2-carboxylic acid, 1-[3-(dimethylamino)propyl]-5,5-di-(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester Chemical Properties
Boiling point 717.7±60.0 °C(Predicted)
density 0.92±0.1 g/cm3(Predicted)
solubility Ethanol: Soluble
pka9.51±0.28(Predicted)
form Liquid
color Colorless to light yellow
Safety Information
MSDS Information
1H-Imidazole-2-carboxylic acid, 1-[3-(dimethylamino)propyl]-5,5-di-(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester Usage And Synthesis
UsesA12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle[1].
References[1] Miao L, et al. Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation. Nat Biotechnol. 2019 Oct;37(10):1174-1185. DOI:10.1038/s41587-019-0247-3
1H-Imidazole-2-carboxylic acid, 1-[3-(dimethylamino)propyl]-5,5-di-(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester Preparation Products And Raw materials
Tag:1H-Imidazole-2-carboxylic acid, 1-[3-(dimethylamino)propyl]-5,5-di-(8Z)-8-heptadecen-1-yl-2,5-dihydro-, ethyl ester(2412492-06-7) Related Product Information
Thieno[2,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-, (9Z,12Z)-9,12-octadecadien-1-yl ester 1-Propanamine, N,N-dimethyl-2,3-bis[(9Z)-9-octadecen-1-yloxy]-, (2R)- 31hP 2-Tetradecanol, 1,1′-[[2-[2-[4-[2-[[2-[2-[bis(2-hydroxytetradecyl)amino]ethoxy]ethyl](2-hydroxytetradecyl)amino]ethyl]-1-piperazinyl]ethoxy]ethyl]imino]bis- DSPE-PEG-OH Heptadecan-9-yl 8-((2-hydroxyethyl)(8-nonyloxy)-8-oxooctyl)amino)octanoate