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| | benzomalvin B Basic information |
| Product Name: | benzomalvin B | | Synonyms: | benzomalvin B;Quinazolino[3,2-a][1,4]benzodiazepine-5,13-dione, 6,7-dihydro-6-methyl-7-(phenylmethylene)-, (7E)-(+)- (9CI) | | CAS: | 157047-97-7 | | MF: | C24H17N3O2 | | MW: | 379.41 | | EINECS: | | | Product Categories: | | | Mol File: | 157047-97-7.mol |  |
| | benzomalvin B Chemical Properties |
| Boiling point | 612.1±65.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | -2.03±0.20(Predicted) | | form | A solid |
| | benzomalvin B Usage And Synthesis |
| Description | Benzomalvin B is a fungal metabolite originally isolated from Penicillium. It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P by 24% in vitro when used at a concentration of 100 μg/ml. | | Uses | Benzomalvin B is the less active analogs of Benzomalvin A. Benzomalvin B is weakly active against substance P[1]. | | References | [1] Sun HH, et al. Benzomalvins, new substance P inhibitors from a Penicillium sp. J Antibiot (Tokyo). 1994;47(5):515-522. DOI:10.7164/antibiotics.47.515 |
| | benzomalvin B Preparation Products And Raw materials |
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