HFI-437

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HFI-437 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
HFI-437 Basic information
Product Name:HFI-437
Synonyms:HFI-437;4H-1-Benzopyran-3-carboxylic acid, 2-(acetylamino)-7-hydroxy-4-(3-quinolinyl)-, ethyl ester
CAS:1110650-74-2
MF:C23H20N2O5
MW:404.42
EINECS:
Product Categories:
Mol File:1110650-74-2.mol
HFI-437 Structure
HFI-437 Chemical Properties
Boiling point 648.981±55.00 °C(Press: 760.00 Torr)(predicted)
density 1.386±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka9.132±0.70(predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
HFI-437 Usage And Synthesis
UsesHFI-437 is a potent non-peptidic insulin-regulated aminopeptidase (IRAP) inhibitor with a Ki of 20 nM. HFI-437 is a cognitive enhancer[1].
References[1] Anthony L Albiston, et al. Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase. FASEB J. 2008 Dec;22(12):4209-17. DOI:10.1096/fj.08-112227
HFI-437 Preparation Products And Raw materials
Tag:HFI-437(1110650-74-2) Related Product Information
tert-butyl 2-amino-4-(pyridin-3-yl)-4H-benzo[h]chromene-3-carboxylate Ethyl 2-amino-7-hydroxy-4-(pyridin-3-yl)-4H-chromene-3-carboxylate HFI-437 ethyl 2-amino-4-(pyridin-3-yl)-4H-benzo[h]chromene-3-carboxylate HFI-419 Tosedostat